Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
666-02-011 ISMRM Abstract

MR Fingerprinting of Parotid Glands at 3.0T: Assessing Repeatability and Influences of Age, Smoking, and RT

Primary: Neuro - Head & Neck/ENT
Secondary: Acquisition & Reconstruction - Quantitative Imaging: relaxometry, multi-parametric, MR Fingerprinting, and synthetic MRI
666-02-011 · Multiparametric Quantitative MR Methods · Thursday, 14 May, 9:25 AM–10:20 AM · Digital Posters Row G
Keywords: MR Fingerprinting Radiotherapy Aging Head & Neck/ENT Head imaging at 3 Tesla (T)
Accepted
George Wang1, Andrew Dupuis 2,3, Parisa Arjmand2, Franco Alonso2, Wassim Malak2,3, Grace Redmon3, Haley Perlow4, Ari Blitz2,5, Daniel A Herzka1,2,6, Mark Griswold2,3,7,8,9, Chaitra Badve3
1Department of Radiology, Case Western Reserve University School of Medicine, Cleveland, United States of America
2Department of Radiology, Case Western Reserve University, Cleveland, United States of America
3Department of Radiology, University Hospitals, Cleveland, United States of America
4Department of Radiation Oncology, University Hospitals, Cleveland, United States of America
5Case Western Reserve University, Cleveland, United States of America
6Case Western Reserve University School of Medicine, Cleveland, United States of America
7Department of Biomedical Engineering, Case Western Reserve University, Cleveland, United States of America
8University Hospitals Cleveland Medical Center, Cleveland, Ohio, United States of America
9Department of Radiology, University Hospitals Cleveland Medical Center, Cleveland, Ohio, United States of America
Presenting Author: Andrew Dupuis

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References

1. Lee A, Choi YJ, Jeon KJ, et al. Impact of physiological parameters on the parotid gland fat fraction in a normal population. Sci Rep. 2023;13(1):990. Published 2023 Jan 18. doi:10.1038/s41598-023-28193-z [doi]
2. Kim JW, Kim JM, Choi ME, et al. Adiponectin is associated with inflammaging and age-related salivary gland lipid accumulation. Aging (Albany NY). 2023;15(6):1840-1858. doi:10.18632/aging.204618 [doi]
3. Ferragut JM, da Cunha MR, Carvalho CA, et al. Epithelial-stromal interactions in salivary glands of rats exposed to chronic passive smoking. Arch Oral Biol. 2011;56(6):580-587. doi:10.1016/j.archoralbio.2010.11.017 [doi]
4. S M, Ramadoss R, Krishnasamy N, S S, Panneer Selvam S, K H. Impact of Tobacco Consumption on Salivary Protein Profiles: A MALDI-TOF Mass Spectrometry Study. Asian Pac J Cancer Prev. 2025;26(5):1483-1489. Published 2025 May 1. doi:10.31557/APJCP.2025.26.5.1483 [doi]
5. Gunning JA, Limesand KH. Chronic Phenotypes Underlying Radiation-Induced Salivary Gland Dysfunction. J Dent Res. 2024;103(8):778-786. doi:10.1177/00220345241252396 [doi]
6. Saito N, Sakai O, Bauer CM, et al. Age-related relaxo-volumetric quantitative magnetic resonance imaging of the major salivary glands. J Comput Assist Tomogr. 2013;37(2):272-278. doi:10.1097/RCT.0b013e31827b4729 [doi]
7. Zhou N, Chu C, Dou X, et al. Early evaluation of radiation-induced parotid damage in patients with nasopharyngeal carcinoma by T2 mapping and mDIXON Quant imaging: initial findings. Radiat Oncol. 2018;13(1):22. Published 2018 Feb 8. doi:10.1186/s13014-018-0970-9 [doi]
8. Ma D, Gulani V, Seiberlich N, et al. Magnetic resonance fingerprinting. Nature. 2013;495(7440):187-192. doi:10.1038/nature11971 [doi]
9. Dupuis A, Chen Y, Hansen M, et al. Quantifying 3D MR fingerprinting (3D-MRF) reproducibility across subjects, sessions, and scanners automatically using MNI atlases. Magn Reson Med. 2024;91(5):2074-2088. doi:10.1002/mrm.29983 [doi]
10. Johansson AK, Johansson A, Unell L, Ekbäck G, Ordell S, Carlsson GE. Self-reported dry mouth in 50- to 80-year-old Swedes: Longitudinal and cross-sectional population studies. J Oral Rehabil. 2020;47(2):246-254. doi:10.1111/joor.12878 [doi]
11. Aggarwal P, Hutcheson KA, Garden AS, et al. Determinants of patient-reported xerostomia among long-term oropharyngeal cancer survivors. Cancer. 2021;127(23):4470-4480. doi:10.1002/cncr.33849 [doi]
12. Wang K, Pearlstein KA, Moon DH, et al. Assessment of Risk of Xerostomia After Whole-Brain Radiation Therapy and Association With Parotid Dose. JAMA Oncol. 2019;5(2):221-228. doi:10.1001/jamaoncol.2018.4951 [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/666-02-011