Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
409-03-001 / 271-01-007 ISMRM Abstract

Repeatability and reproducibility of knee cartilage T1ρ and T2 mapping: A multi-site multi-vendor study by QMIC

Primary: Musculoskeletal - Cartilage
Secondary: Acquisition & Reconstruction - Quantitative Imaging: relaxometry, multi-parametric, MR Fingerprinting, and synthetic MRI
409-03-001 · Quantitative Imaging: Applications · Tuesday, 12 May, 1:40 PM–3:30 PM · Meeting Room 2.40
271-01-007 · ISMRM AMPC Selected Posters · Sunday, 10 May, 7:00 AM–2:00 PM · Traditional Posters
Keywords: Cartilage Quantitative Imaging T1rho and T2 mapping MSK Relaxometry phantom QMIC
Accepted
Zhiyuan Zhang1,2,3, Xinyan Jian 1,2,3, Jeehun Kim1,3, Richard Lartey1,3, Kihwan Kim1,3,4, Patrick Y Yeh1,3, Mei Li1,3, Nancy Obuchowski4, Carl Winalski1,3,4, Brian J Soher5, Virginia B Kraus6, Qi Peng7, Morgan H Jones8, Stacy E Smith9, Feliks Kogan10, Jing Liu11, Thomas M Link11, Daniel R Thedens12, Donald D Anderson13, Michael A Samaan14, Peter A Hardy15, Brian Pietrosimone16, Majid Chalian17, Qin Qin17, Bruce D Beynnon18, Jiming Zhang19, Niccolo M Fiorentino20, Edwin H Oei21, Shivraman Giri22, maggie fung23, Yansong Zhao24, Jason Kim25
1Program of Advanced Musculoskeletal Imaging (PAMI), Cleveland Clinic, Cleveland, United States of America
2Department of Biomedical Engineering, Case Western Reserve University, Cleveland, United States of America
3Department of Biomedical Engineering, Cleveland Clinic Research, Cleveland Clinic, Cleveland, United States of America
4Department of Diagnostic Radiology, Diagnostics Institute, Cleveland Clinic, Cleveland, United States of America
5Department of Radiology, Center for Advanced MR Development, Duke University Medical Center, Durham, United States of America
6Duke University School of Medicine, Durham, United States of America
7Department of Radiology, Albert Einstein College of Medicine, Bronx, United States of America
8Orthopedic and Arthritis Center for Outcomes Research and Section of Sports Medicine, Department of Orthopedic Surgery, Brigham and Women's Hospital and Harvard Medical School, Boston, United States of America
9Department of Radiology, Brigham and Women's Hospital and Harvard Medical School, Boston, United States of America
10Department of Radiology, Stanford University, Stanford, United States of America
11Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, United States of America
12Department of Radiology, University of Iowa, Iowa City, United States of America
13Department of Orthopedics and Rehabilitation, University of Iowa, Iowa City, United States of America
14Department of Kinesiology & Health Promotion, University of Kentucky, Lexington, United States of America
15Department of Radiology, University of Kentucky, Lexington, United States of America
16Department of Exercise and Sport Science, College of Arts and Sciences, University of North Carolina at Chapel Hill, Chapel Hill, United States of America
17Department of Radiology, University of Washington, Seattle, United States of America
18Department of Orthopaedics and Rehabilitation, University of Vermont, Burlington, United States of America
19Department of Radiology Oncology & Medical Physics, University of Vermont Medical Center, Burlington, United States of America
20Department of Mechanical Engineering, University of Vermont, Burlington, United States of America
21Department of Radiology and Nuclear Medicine, Erasmus MC - University Medical Center, Netherlands
22Siemens Medical Solutions USA, Inc., Malvern, United States of America
23MR Clinical Solutions, GE HealthCare, San Ramon, United States of America
24Philips Healthcare (Cambridge), Cambridge, United States of America
25Arthritis Foundation, Atlanta, United States of America
Presenting Author: Xinyan Jian

Synopsis

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References

1. Link TM, Neumann J, Li X. Prestructural cartilage assessment using MRI. J Magn Reson Imaging. 2017;45(4):949-965. doi:10.1002/jmri.25554 [doi]
2. Li X, Benjamin Ma C, Link TM, et al. In vivo T(1rho) and T(2) mapping of articular cartilage in osteoarthritis of the knee using 3 T MRI. Osteoarthritis Cartilage. 2007;15(7):789-797. doi:10.1016/j.joca.2007.01.011 [doi]
3. Chalian M, Li X, Guermazi A, et al. The QIBA Profile for MRI-based Compositional Imaging of Knee Cartilage. Radiology. 2021;301(2):423-432. doi:10.1148/radiol.2021204587 [doi]
4. Li X, Han ET, Busse RF, Majumdar S. In vivo T(1ρ) mapping in cartilage using 3D magnetization-prepared angle-modulated partitioned k-space spoiled gradient echo snapshots (3D MAPSS). Magnetic resonance in medicine. 2008;59(2):298-307. Epub 2008/01/30. doi: 10.1002/mrm.21414. [doi]
5. Kim J, Mamoto K, Lartey R, et al. Multi-vendor multi-site T1ρ and T2 quantification of knee cartilage. Osteoarthritis Cartilage. 2020;28(12):1539-1550. doi:10.1016/j.joca.2020.07.005 [doi]
6. Statton BK, Smith J, Finnegan ME, Koerzdoerfer G, Quest RA, Grech-Sollars M. Temperature dependence, accuracy, and repeatability of T1 and T2 relaxation times for the ISMRM/NIST system phantom measured using MR fingerprinting. Magn Reson Med. 2022;87(3):1446-1460. doi:10.1002/mrm.29065 [doi]
7. Jeehun Kim et al., Multi-site Multi-vendor Randomized Controlled Trial of Quantitative Knee MRI using a Novel MSK Relaxometry Phantom. In: 2025 ISMRM & ISMRT Annual Meeting & Exhibition, Hawaii, 2025. (abstract 8992).
8. Gaj S, Yang M, Nakamura K, Li X. Automated cartilage and meniscus segmentation of knee MRI with conditional generative adversarial networks. Magn Reson Med. 2020;84(1):437-449. doi:10.1002/mrm.28111 [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/409-03-001