Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
665-03-001 ISMRM Abstract

Time-Dependent Diffusion MRI Reveals Microstructural Differences Between Early Progression and Pseudoprogression in Glioma

Primary: Neuro - Tumors
Secondary: Brain Function and fMRI - fMRI Analysis
665-03-001 · fMRI: Applications in Neurology and Psychiatry III · Thursday, 14 May, 1:40 PM–2:35 PM · Digital Posters Row F
Keywords: Time-dependent diffusion MRI Microstructural parameters Pseudoprogression Early progression
Accepted
Junwei Chang 1, Yuhui Xiong2, Jing Zhang1
1Department of Magnetic Resonance, Lanzhou, China
2GE HealthCare MR Research, Beijing, China
Presenting Author: Junwei Chang

Synopsis

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References

1. Li, X., et al., Targeting DNM1L/DRP1-FIS1 axis inhibits high-grade glioma progression by impeding mitochondrial respiratory cristae remodeling. J Exp Clin Cancer Res, 2024. 43(1): p. 273.
2. Zikou, A., et al., Radiation Necrosis, Pseudoprogression, Pseudoresponse, and Tumor Recurrence: Imaging Challenges for the Evaluation of Treated Gliomas. Contrast Media Mol Imaging, 2018. 2018: p. 6828396.
3. Chen, J., et al., Apparent diffusion coefficient and tissue stiffness are associated with different tumor microenvironment features of hepatocellular carcinoma. Eur Radiol, 2024. 34(11): p. 6980-6991.
4. Zhu, A., et al., Revealing tumor microstructure with oscillating diffusion encoding MRI in pre-surgical and post-treatment glioma patients. Magn Reson Med, 2023. 90(5): p. 1789-1801.
5. Gore, J.C., et al., Characterization of tissue structure at varying length scales using temporal diffusion spectroscopy. NMR Biomed, 2010. 23(7): p. 745-56.
6. Xu, J., Probing neural tissues at small scales: Recent progress of oscillating gradient spin echo (OGSE) neuroimaging in humans. J Neurosci Methods, 2021. 349: p. 109024.
7. Wen, P.Y., et al., RANO 2.0: Update to the Response Assessment in Neuro-Oncology Criteria for High- and Low-Grade Gliomas in Adults. J Clin Oncol, 2023. 41(33): p. 5187-5199.
8. Nilsson, M., et al., Imaging brain tumour microstructure. Neuroimage, 2018. 182: p. 232-250.
9. Zhang, H., et al., Histological and molecular classifications of pediatric glioma with time-dependent diffusion MRI-based microstructural mapping. Neuro Oncol, 2023. 25(6): p. 1146-1156.

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/665-03-001