Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
566-01-014 ISMRM Abstract

Impact of Modifiable Lifestyle Factors on Dementia Subtypes and Brain Structural Changes in Individuals with Impaired Kidney

Primary: Neuro - Alzheimer's Disease
Secondary: Cross-Organ
566-01-014 · Detectable Changes in Dementia · Wednesday, 13 May, 8:20 AM–9:15 AM · Digital Posters Row G
Keywords: Dementia Magnetic Resonance Imaging (MRI) Kidney diseases Healthy lifestyle Renal insufficiency.
Accepted
Xintian Ren 1, Li Yu2, Wenbo Yang2,3, Lijun Song2,3, Mingan Li2,3, Xiaoyan Bai2,3, Boyan Xu4,5,6, Zhenghan Yang2,7, Zhenchang Wang2, Han Lv2, Hao Wang2,7,8, Min Li1,2
1Clinical Epidemiology and EBM Unit, Beijing Friendship Hospital, Capital Medical University, beijing, China
2Beijing Friendship Hospital, Capital Medical University, beijing, China
3Beijing freindship hospital, Capital Medical University, Beijing, China
4MR Research China, GE Healthcare, Beijing, China
5MR Research, Beijing, China
6MR Research, GE Healthcare, Beijing, China
7Capital Medical University Affiliated Beijing Friendship Hospital, Beijing, China
8Department of Radiology, Beijing Friendship Hospital, Capital Medical University, beijing, China
Presenting Author: Xintian Ren

Synopsis

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References

1. GBD 2019 Dementia Forecasting Collaborators. Estimation of the global prevalence of dementia in 2019 and forecasted prevalence in 2050: an analysis for the Global Burden of Disease Study 2019. Lancet Public Health. 2022 Feb;7(2):e105-e125. doi: 10.1016/S2468-2667(21)00249-8. Epub 2022 Jan 6. PMID: 34998485; [doi] [pmid]
2. Madigan S, Deneault AA, Racine N, et al. Adverse childhood experiences: a meta-analysis of prevalence and moderators among half a million adults in 206 studies. World Psychiatry. 2023 Oct;22(3):463-471. doi: 10.1002/wps.21122. PMID: 37713544; PMCID: [doi] [pmid]
3. Xu H, Eriksdotter M, Garcia-Ptacek S, et al. Acute Kidney Injury and Its Association With Dementia and Specific Dementia Types: Findings From a Population-Based Study in Sweden. Neurology. 2024 Sep 24;103(6):e209751. doi: 10.1212/WNL.0000000000209751. Epub 2024 Aug 22. PMID: 39173107; [doi] [pmid]
4. Drew DA, Weiner DE, Sarnak MJ. Cognitive Impairment in CKD: Pathophysiology, Management, and Prevention. Am J Kidney Dis. 2019 Dec;74(6):782-790. doi: 10.1053/j.ajkd.2019.05.017. Epub 2019 Aug 1. PMID: 31378643; PMCID: [doi] [pmid]
5. Lipnicki DM, Crawford J, Kochan NA, et al. Risk Factors for Mild Cognitive Impairment, Dementia and Mortality: The Sydney Memory and Ageing Study. J Am Med Dir Assoc. 2017 May 1;18(5):388-395. doi: 10.1016/j.jamda.2016.10.014. Epub 2016 Dec 31. [doi]
6. Wang S, Wang J, Dove A, et al. Association of impaired kidney function with dementia and brain pathologies: A community-based cohort study. Alzheimers Dement. 2023 Jul;19(7):2765-2773. doi: 10.1002/alz.12910. Epub 2022 Dec 26. PMID: 36571791; PMCID: [doi] [pmid]
7. Scheppach JB, Wu A, Gottesman RF, et al. Association of Kidney Function Measures With Signs of Neurodegeneration and Small Vessel Disease on Brain Magnetic Resonance Imaging: The Atherosclerosis Risk in Communities (ARIC) Study. Am J Kidney Dis. 2023 Mar;81(3):261-269.e1. doi: 10.1053/j.ajkd.2022.07.013. Epub 2022 Sep 27. PMID: 36179945; [doi] [pmid]
8. Sudlow C, Gallacher J, Allen N, et al. UK biobank: an open access resource for identifying the causes of a wide range of complex diseases of middle and old age. PLoS Med. 2015 Mar 31;12(3):e1001779. doi: 10.1371/journal.pmed.1001779. PMID: 25826379; [doi] [pmid]
9. Wang X, Ma H, Li X, et al. Association of Cardiovascular Health With Life Expectancy Free of Cardiovascular Disease, Diabetes, Cancer, and Dementia in UK Adults. JAMA Intern Med. 2023;183(4):340-349. doi:10.1001/jamainternmed.2023.0015 [doi]
10. Thompson DJ, Wells D, Selzam S, et al. UK Biobank release and systematic evaluation of optimised polygenic risk scores for 53 diseases and quantitative traits. medRxiv. 2022. doi:https://doi.org/10.1101/2022.06.16.22276246. [doi]
11. Bycroft C, Freeman C, Petkova D, et al. The UK Biobank resource with deep phenotyping and genomic data. Nature. 2018;562(7726):203-209. doi:10.1038/s41586-018-0579-z [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/566-01-014