Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
404-03-008 ISMRM Abstract

Choroid Plexus Enlargement is Linked to a Periventricular Gradient of White Matter Injury in RRMS

Primary: Neuro - Neuroinflammation
Secondary: Analysis Methods - Segmentation and Detection
404-03-008 · Multiscale MRI in Neuroinflammation · Tuesday, 12 May, 1:40 PM–3:30 PM · Ballroom East
Keywords: Multiple Sclerosis Choroid plexus morphometry White matter microstructure Immune cells
Accepted
xiaoya chen1, Robert Neil 2, Li yongmei3
1the department of radiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China
2Queen's Medical Research Institute, University of Edinburgh, United Kingdom
3The First Affiliated Hospital of Chongqing Medical University, Chongqing, China
Presenting Author: Robert Neil

Synopsis

Motivation:
Goals:
Approach:
Results:
Full abstract & presentation

The full text, figures, and any recorded presentation for this abstract are not shown here. Log in if you are a member or registered attendee with access.

Full abstracts, figures, and presentations for Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition are available to registered attendees. This content becomes freely available to the public roughly two years after the meeting.

To request or purchase access, contact the ISMRM Central Office at info@ismrm.org.

Log in

References

1. Ricigliano VAG, Morena E, Colombi A, Tonietto M, Hamzaoui M, Poirion E, Bottlaender M, Gervais P, Louapre C, Bodini B, Stankoff B. Choroid Plexus Enlargement in Inflammatory Multiple Sclerosis: 3.0-T MRI and Translocator Protein PET Evaluation. Radiology 2021;301(1):166-177. doi: 10.1148/radiol.2021204426 [doi]
2. Lazarevic I, Soldati S, Mapunda JA, Rudolph H, Rosito M, de Oliveira AC, Enzmann G, Nishihara H, Ishikawa H, Tenenbaum T, Schroten H, Engelhardt B. The choroid plexus acts as an immune cell reservoir and brain entry site in experimental autoimmune encephalomyelitis. Fluids Barriers CNS 2023;20(1):39. doi: 10.1186/s12987-023-00441-4 [doi]
3. Tonietto M, Poirion E, Lazzarotto A, Ricigliano V, Papeix C, Bottlaender M, Bodini B, Stankoff B. Periventricular remyelination failure in multiple sclerosis: a substrate for neurodegeneration. Brain 2023;146(1):182-194. doi: 10.1093/brain/awac334 [doi]
4. Bergsland N, Dwyer MG, Jakimovski D, Tavazzi E, Weinstock-Guttman B, Zivadinov R. Choroid plexus enlargement is associated with future periventricular neurodegeneration in multiple sclerosis. Mult Scler Relat Disord 2024;87:105668. doi: 10.1016/j.msard.2024.105668 [doi]
5. Eisma JJ, McKnight CD, Hett K, Elenberger J, Han CJ, Song AK, Considine C, Claassen DO, Donahue MJ. Deep learning segmentation of the choroid plexus from structural magnetic resonance imaging (MRI): validation and normative ranges across the adult lifespan. Fluids Barriers CNS 2024;21(1):21. doi: 10.1186/s12987-024-00525-9 [doi]
6. 17. Liu C, Zhuo Z, Qu L, Jin Y, Hua T, Xu J, Tan G, Li Y, Duan Y, Wang T, Zhang Z, Zhang Y, Chen R, Yu P, Zhang P, Shi Y, Zhang J, Tian D, Li R, Zhang X, Shi F, Wang Y, Jiang J, Carass A, Liu Y, Ye C. DeepWMH: A deep learning tool for accurate white matter hyperintensity segmentation without requiring manual annotations for training. Sci Bull (Beijing) 2024;69(7):872-875. doi: 10.1016/j.scib.2024.01.034 [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/404-03-008