Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
361-06-008 ISMRM Abstract

Microstructural Assessment of Oral Squamous Cell Carcinoma Using Time-Dependent Diffusion MRI

Primary: Diffusion - Microstructure
Secondary: Acquisition & Reconstruction - Quantitative Imaging: head and neck
361-06-008 · Quantitative Imaging: Head and Neck II · Monday, 11 May, 5:05 PM–6:00 PM · Digital Posters Row B
Keywords: Microstructure Time-dependent diffusion MRI Head and Neck Histopathology Quantitative imaging biomarkers
Accepted
Carlijn Jamila Guichelaar 1, Minea M Jokivuolle2,3, Rémi van der Woude1, Hilde J. G Smits1, Mark Schuiveling4, Gerben E Breimer4, Annette Van der Toorn5, Kristoffer H Madsen6,7,8, Henrik Lundell6,9, Faisal Mahmood2,3, Marielle Philippens1
1Department of Radiotherapy, University Medical Center Utrecht, Utrecht, Netherlands
2Laboratory of Radiation Physics, Department of Oncology, Odense University Hospital, Odense, Denmark
3Department of Clinical Research, University of Southern Denmark, Odense, Denmark
4Department of Pathology, University Medical Center Utrecht, Utrecht, Netherlands
5Translational Neuroimaging Group, Center for Image Sciences, University Medical Center Utrecht, Utrecht, Netherlands
6Danish Research Centre for Magnetic Resonance, Department of Radiology and Nuclear Medicine, Copenhagen University Hospital - Amager and Hvidovre, Copenhagen, Denmark
7Department of Applied Mathematics and Computer Science, Technical University of Denmark, Kgs. Lyngby, Denmark
8Department of Radiology, Zealand University Hospital, Køge, Denmark
9MR Section, Department of Health Technology, Technical University of Denmark, Kgs. Lyngby, Denmark
Presenting Author: Carlijn Jamila Guichelaar

Synopsis

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References

1. Koh DM, Collins DJ. Diffusion-weighted MRI in the body: applications and challenges in oncology. AJR Am J Roentgenol. 2007 Jun;188(6):1622-35. doi: 10.2214/AJR.06.1403. PMID: 17515386. [doi] [pmid]
2. Jokivuolle M, Mahmood F, Madsen KH, Harbo FSG, Johnsen L, Lundell H. Assessing tumor microstructure with time-dependent diffusion imaging: Considerations and feasibility on clinical MRI and MRI-Linac. Med Phys. 2025 Jan;52(1):346-361. doi: 10.1002/mp.17453. PMID: 39387639. [doi] [pmid]
3. Jokivuolle M, Lundell H, Madsen KH, Poulsen FR, Petersen JK, Grønhøj MH, Harbo FSG, Wirenfeldt M, Dahlrot RH, Ewald JD, Bisgaard ALH, Mahmood F. Mapping cell density and hypoxia in glioblastoma using time-dependent diffusion MRI: improved cell density assessment compared to conventional diffusion metrics. Phys Med Biol. 2025 Jul 17;70(14). doi: 10.1088/1361-6560/adece1. PMID: 40623432. [doi] [pmid]
4. Rumberger JL, Baumann E, Hirsch P, Janowczyk A, Zlobec I, Kainmueller D. Panoptic segmentation with highly imbalanced semantic labels. IEEE International Symposium on Biomedical Imaging Challenges. 2022. doi: 10.1109/ISBIC56247.2022.9854551. [doi]
5. Baumann E, Dislich B, Rumberger JL, Nagtegaal ID, Martinez MR, Zlobec I. HoVer-NeXt: A Fast Nuclei Segmentation and Classification Pipeline for Next Generation Histopathology. Proceedings of The 7nd International Conference on Medical Imaging with Deep Learning, PMLR 250:61-86, 2024.

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/361-06-008