Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
661-01-003 ISMRM Abstract

Simplified Method for Assessing Blood-CSF Barrier Function in Humans using multi-TE / PLD pCASL

Primary: Neuro - Neurofluids
Secondary: Analysis Methods - Data Processing
661-01-003 · Advances in ASL · Thursday, 14 May, 8:30 AM–9:25 AM · Digital Posters Row B
Keywords: Blood csf barrier mappimg Multi-TE ASL CSF Barrier Dynamics TE-based weighting Single Kernel Delivery
Accepted
HUSSAINI AHMED 1, Antonio C Senra Filho1, Sara Monteiro2, Patricia Figueiredo2, Andre M Paschoal3
1University of Campinas, SP. Brazil, Lab of Advance MRI., Campinas, Brazil
2Institute for Systems and Robotics – Lisboa and Department of Bioengineering, Instituto Superior Técnico, Universidade de Lisboa, Lisbon, Portugal
3University of Campinas, Campinas, Brazil
Presenting Author: HUSSAINI AHMED

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References

1. P. G. Evans et al., “Non-Invasive MRI of Blood-Cerebrospinal Fluid Barrier Function,” Nature Communications, no. 2020, pp. 1–11, 2020, doi: 10.1038/s41467-020-16002-4. [doi]
2. H. Lee et al., “Choroid plexus tissue perfusion and blood to CSF barrier function in rats measured with continuous arterial spin labeling,” NeuroImage, vol. 261, p. 119512, Nov. 2022, doi: 10.1016/j.neuroimage.2022.119512. [doi]
3. LA Rivera-Rivera et al., Four-dimensional flow MRI for quantitative assessment of cerebrospinal fluid dynamics: Status and opportunities. NMR Biomed. 2024 Jul;37(7):e5082. doi: 10.1002/nbm.5082. [doi]
4. T Vikner et al., CSF dynamics throughout the ventricular system using 4D flow MRI: associations to arterial pulsatility, ventricular volumes, and age. Fluids Barriers CNS. 2024 Aug 30;21(1):68. doi: 10.1186/s12987-024-00570-4. [doi]
5. L. Petitclerc et al., “Ultra-long-TE arterial spin labeling reveals rapid and brain-wide blood-to-CSF water transport in humans,” NeuroImage, vol. 245, no. September, p. 118755, Dec. 2021, doi: 10.1016/j.neuroimage.2021.118755. [doi]
6. Y. Wu et al., “Rapid Tissue–CSF Water Exchange in the Human Brain Revealed by Magnetization Transfer Indirect Spin Labeling,” Sep. 02, 2025, Radiology and Imaging. doi: 10.1101/2025.08.28.25334379. [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/661-01-003