460-06-008 ISMRM Abstract

Time-Dependent Diffusion MRI of Neurofluid–Microstructure Coupling in Obstructive Sleep Apnea

Primary: Neuro - Neurofluids

Secondary: Diffusion - Diffusion Analysis & Visualization

460-06-008 · Imaging the Brain’s Microenvironment: From Glymphatics to Cognition · Tuesday, 12 May, 4:55 PM–5:50 PM · Digital Posters Row A

Keywords: Neurofluids White Matter Sleep Glymphatic system Time-dependent diffusion MRI

Accepted

Toshiaki Taoka ^1,2, Kunihiro Iwamoto³, Rintaro Ito^1,2, Seiko Miyata³, Rei Nakamichi², Toshiki Nakane², Hiroshige Fujishiro³, Masashi Ikeda³, Kazushige Ichikawa⁴, Akifumi Kamiunten⁵, 伸保市之瀬⁵, Shinji Naganawa²

¹Department of Innovative Biomedical Visualization, Nagoya University Graduate School of Medicine, Nagoya, Japan

²Department of Radiology, Nagoya University Graduate School of Medicine, Nagoya, Japan

³Department of Psychiatry, Nagoya University Graduate School of Medicine, Nagoya, Japan

⁴Department of Radiology, Nagoya University Hospital, Nagoya, Japan

⁵Canon Medical Systems Corporation, Otawara-shi, Japan

Presenting Author: Toshiaki Taoka

Synopsis

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References

1. Taoka T, Iwamoto K, Miyata S, Ito R, Kamagata K, Nakamichi R, et al. Contribution of white matter microstructure to diffusion tensor image analysis along perivascular space in obstructive sleep apnea. Jpn J Radiol. 2025.10.1007/s11604-025-01838-x

2. Taoka T, Iwamoto K, Miyata S, Ito R, Nakamichi R, Nakane T, et al. MR Imaging Indices for Brain Interstitial Fluid Dynamics and the Effects of Orexin Antagonists on Sleep. Magn Reson Med Sci. 2025.10.2463/mrms.mp.2024-0176

3. Taoka T, Ito R, Nakamichi R, Nakane T, Kawai H, Naganawa S. Diffusion Tensor Image Analysis ALong the Perivascular Space (DTI-ALPS): Revisiting the Meaning and Significance of the Method. Magn Reson Med Sci. 2024;23(3):268–90.10.2463/mrms.rev.2023-0175

4. Taoka T, Masutani Y, Kawai H, Nakane T, Matsuoka K, Yasuno F, et al. Evaluation of glymphatic system activity with the diffusion MR technique: diffusion tensor image analysis along the perivascular space (DTI-ALPS) in Alzheimer's disease cases. Jpn J Radiol. 2017;35(4):172–8.10.1007/s11604-017-0617-z

5. Taoka T, Naganawa S. Glymphatic imaging using MRI. J Magn Reson Imaging. 2020;51(1):11–24.10.1002/jmri.26892

6. Drobnjak I, Zhang H, Ianus A, Kaden E, Alexander DC. PGSE, OGSE, and sensitivity to axon diameter in diffusion MRI: Insight from a simulation study. Magn Reson Med. 2016;75(2):688–700.10.1002/mrm.25631

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/460-06-008