Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
560-01-011 ISMRM Abstract

Is It Resonating? A Framework for Deciding When (and When Not) to Harmonize Multi-Site QSM/R2* Data

Accepted
Elena Kovacevic 1, Nashwan Naji2, Lindsay Munroe1, Poljanka Johnson1, Dlorah Lyne R Agama1, Zhuoran Wang1, Annette Lam1, Bretta Russell-Schulz1, Irene M Vavasour1, Joshua D Lee1, Yunyan Zhang3, Roger Tam1, Jiwon Oh4, Alexandre Prat5, Alan H Wilman2, Anthony Traboulsee1, Shannon Kolind1
1University of British Columbia, Vancouver, Canada
2University of Alberta, Edmonton, Canada
3University of Calgary, Calgary, Canada
4University of Toronto, Toronto, Canada
5University of Montreal, Montreal, Canada
Presenting Author: Elena Kovacevic

Synopsis

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References

1. Bayer JMM, Thompson PM, Ching CRK, Liu M, Chen A, Panzenhagen AC, et al. Site effects how-to and when: An overview of retrospective techniques to accommodate site effects in multi-site neuroimaging analyses. Front Neurol. 2022 Oct 31;13:923988. https://doi.org/10.3389/fneur.2022.923988 [doi]
2. Richter S, Winzeck S, Correia MM, Kornaropoulos EN, Manktelow A, Outtrim J, et al. Validation of cross-sectional and longitudinal ComBat harmonization methods for magnetic resonance imaging data on a travelling subject cohort. Neuroimage Rep. 2022 Dec;2(4):100136. https://doi.org/10.1016/j.ynirp.2022.100136 [doi]
3. Oh J, Arbour N, Giuliani F, Guenette M, Kolind S, Lynd L, et al. The Canadian prospective cohort study to understand progression in multiple sclerosis (CanProCo): rationale, aims, and study design. BMC Neurol. 2021 Dec;21(1):418. https://doi.org/10.1186/s12883-021-02447-7 [doi]
4. Naji N, Lauzon ML, Seres P, Stolz E, Frayne R, Lebel C, et al. Multisite reproducibility of quantitative susceptibility mapping and effective transverse relaxation rate in deep gray matter at 3 T using locally optimized sequences in 24 traveling heads. NMR Biomed. 2022 Nov;35(11):e4788. https://doi.org/10.1002/nbm.4788 [doi]
5. Mori, S, Wakana, S, Zijl, P. C. M. van, Nagae-Poetscher, L. M. MRI Atlas of Human White Matter. Elsevier. 2005;
6. Tustison NJ, Cook PA, Holbrook AJ, Johnson HJ, Muschelli J, Devenyi GA, et al. The ANTsX ecosystem for quantitative biological and medical imaging. Sci Rep. 2021 Apr 27;11(1):9068. https://doi.org/10.1038/s41598-021-87564-6 [doi]
7. Beaulieu LD, Flamand VH, Massé-Alarie H, Schneider C. Reliability and minimal detectable change of transcranial magnetic stimulation outcomes in healthy adults: A systematic review. Brain Stimulat. 2017 Mar;10(2):196–213. https://doi.org/10.1016/j.brs.2016.12.008 [doi]
8. Ravanfar P, Loi SM, Syeda WT, Van Rheenen TE, Bush AI, Desmond P, et al. Systematic Review: Quantitative Susceptibility Mapping (QSM) of Brain Iron Profile in Neurodegenerative Diseases. Front Neurosci. 2021 Feb 18;15:618435. https://doi.org/10.3389/fnins.2021.618435 [doi]
9. Oh SS, Oh S, Nam Y, Han D, Stafford RB, Hwang J, et al. Improved susceptibility weighted imaging method using multi‐echo acquisition. Magn Reson Med. 2014 Aug;72(2):452–8. https://doi.org/10.1002/mrm.24940 [doi]
10. Juchem C, Nixon TW, McIntyre S, Rothman DL, De Graaf RA. Magnetic field homogenization of the human prefrontal cortex with a set of localized electrical coils. Magn Reson Med. 2010 Jan;63(1):171–80. https://doi.org/10.1002/mrm.22164 [doi]
11. Leutritz T, Seif M, Helms G, Samson RS, Curt A, Freund P, et al. Multiparameter mapping of relaxation ( R1 , R2 *), proton density and magnetization transfer saturation at 3 T : A multicenter dual‐vendor reproducibility and repeatability study. Hum Brain Mapp. 2020 Oct 15;41(15):4232–47. https://doi.org/10.1002/hbm.25122 [doi]

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