Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
370-02-013 ISMRM Abstract

Serum PTX3 Levels Correlate with Surface Irregularity and Focal Enhancement in Carotid Vulnerable Plaques

Accepted
Tingting Li 1, jianxiu lian2,3,4, Wei Yu1
1Beijing Anzhen Hospital, Capital Medical University, Beijing, China
2Philips Healthcare, Guangzhou, China
3Clinical and Technical Support, Philips Healthcare (Beijing), Beijing, China
4Philips Healthcare (Beijing), Beijing, China
Presenting Author: Tingting Li

Synopsis

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References

1. Van Dam-Nolen D H K, Truijman M T B, Van Der Kolk A G, et al. Carotid Plaque Characteristics Predict Recurrent Ischemic Stroke and TIA: The PARISK (Plaque At RISK) Study[J]. JACC Cardiovasc. Imaging, 2022, 15(10): 1715-1726. doi: 10.1016/j.jcmg.2022.04.003. [doi]
2. Saba L, Loewe C, Weikert T, et al. State-of-the-art CT and MR imaging and assessment of atherosclerotic carotid artery disease: standardization of scanning protocols and measurements-a consensus document by the European Society of Cardiovascular Radiology (ESCR)[J]. Eur. Radiol., 2023, 33(2): 1063-1087. doi: 10.1007/s00330-022-09024-7. [doi]
3. Soeki T, Sata M. Inflammatory Biomarkers and Atherosclerosis[J]. Int. Heart. J., 2016, 57(2): 134-139. doi: 10.1536/ihj.15-346. [doi]
4. Zhang Y, Hu H, Liu C, et al. Serum pentraxin 3 as a biomarker for prognosis of acute minor stroke due to large artery atherosclerosis[J]. Brain Behav., 2021, 11(1): e01956. doi: 10.1002/brb3.1956. [doi]
5. Rolph M S, Zimmer S, Bottazzi B, et al. Production of the Long Pentraxin PTX3 in Advanced Atherosclerotic Plaques[J]. Arterioscler. Thromb. Vasc. Biol., 2002, 22(5): e10-e14. doi: 10.1161/01.ATV.0000015595.95497.2F. [doi]
6. Millon A, Boussel L, Brevet M, et al. Clinical and Histological Significance of Gadolinium Enhancement in Carotid Atherosclerotic Plaque[J]. Stroke, 2012, 43(11): 3023-3028. doi: 10.1161/STROKEAHA.112.662692. [doi]
7. Iwata A, Miura S ichiro, Tanaka T, et al. Plasma pentraxin-3 levels are associated with coronary plaque vulnerability and are decreased by statin[J]. Coron. Artery Dis., 2012, 23(5): 315-321. doi: 10.1097/MCA.0b013e328352ffec. [doi]
8. Casula M, Montecucco F, Bonaventura A, et al. Update on the role of Pentraxin 3 in atherosclerosis and cardiovascular diseases[J]. Vascul. Pharmacol., 2017, 99: 1-12. doi: 10.1016/j.vph.2017.10.003. [doi]

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