Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
401-03-007 ISMRM Abstract

Unlocking the Spin-Lock: Open-Source and Vendor-Agnostic Cardiac T1ρ Fingerprinting with Pulseq

Primary: Contrast Mechanisms - Novel Contrast Mechanisms
Secondary: Acquisition & Reconstruction - Open source software, sequences, and reconstruction algorithms
401-03-007 · End-to-End Software Innovation · Tuesday, 12 May, 1:40 PM–3:30 PM · Hall 1A
Keywords: MR Fingerprinting Cardiac MRI Open-source software Spin-Lock T1rho
Accepted
Maximilian Gram 1,2, Tom Griesler3,4, Sydney Kaplan3,4, Jannik Stebani2, Ivaylo Angelov2, Petra Albert1,2, Martin Blaimer2,5, Tobias Wech6, Qingping Chen7, Xiang Wang7, Maxim Zaitsev7, Jesse Hamilton3,4, Peter M Jakob2, Nicole Seiberlich3,4, Peter Nordbeck1
1Department of Internal Medicine I, University Hospital Würzburg, Würzburg, Germany
2Experimental Physics 5, University of Würzburg, Würzburg, Germany
3Department of Biomedical Engineering, University of Michigan, Ann Arbor, United States of America
4Department of Radiology, University of Michigan, Ann Arbor, United States of America
5Fraunhofer Institute for Integrated Circuits IIS, Würzburg, Germany
6Department of Diagnostic and Interventional Radiology, University Hospital Würzburg, Würzburg, Germany
7Division of Medical Physics, Department of Radiology, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany
Presenting Author: Maximilian Gram

Synopsis

Motivation:
Goals:
Approach:
Results:
Full abstract & presentation

The full text, figures, and any recorded presentation for this abstract are not shown here. Log in if you are a member or registered attendee with access.

Full abstracts, figures, and presentations for Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition are available to registered attendees. This content becomes freely available to the public roughly two years after the meeting.

To request or purchase access, contact the ISMRM Central Office at info@ismrm.org.

Log in

References

1. Bustin A, Witschey WRT, van Heeswijk RB, Cochet H, Stuber M. Magnetic resonance myocardial T1ρ mapping: Technical overview, challenges, emerging developments, and clinical applications. J Cardiovasc Magn Reson. 2023 Jun 19;25(1):34. doi: 10.1186/s12968-023-00940-1. PMID: 37331930 [doi] [pmid]
2. Charagundla SR, Borthakur A, Leigh JS, Reddy R. Artifacts in T(1rho)-weighted imaging: correction with a self-compensating spin-locking pulse. J Magn Reson. 2003 May;162(1):113-21. doi: 10.1016/s1090-7807(02)00197-0. PMID: 12762988 [doi] [pmid]
3. Witschey WR 2nd, Borthakur A, Elliott MA, Mellon E, Niyogi S, Wallman DJ, Wang C, Reddy R. Artifacts in T1rho-weighted imaging: compensation for B(1) and B(0) field imperfections. J Magn Reson. 2007 May;186(1):75-85. doi: 10.1016/j.jmr.2007.01.015. PMID: 17291799 [doi] [pmid]
4. Gram M, Seethaler M, Gensler D, Oberberger J, Jakob PM, Nordbeck P. Balanced spin-lock preparation for B1 -insensitive and B0 -insensitive quantification of the rotating frame relaxation time T1ρ. Magn Reson Med. 2021 May;85(5):2771-2780. doi: 10.1002/mrm.28585. PMID: 33166009 [doi] [pmid]
5. Wan C, Gram M, He W, Xu Z, Chen Q, Littin S, Lange T, Zaitsev M. Quadruple-refocused spin-locking: A robust method for high-amplitude T1ρ imaging. Magn Reson Med. 2025 Nov;94(5):2023-2037. doi: 10.1002/mrm.30621. PMID: 40580517 [doi] [pmid]
6. Schuenke P, Koehler C, Korzowski A, Windschuh J, Bachert P, Ladd ME, Mundiyanapurath S, Paech D, Bickelhaupt S, Bonekamp D, Schlemmer HP, Radbruch A, Zaiss M. Adiabatically prepared spin-lock approach for T1ρ-based dynamic glucose enhanced MRI at ultrahigh fields. Magn Reson Med. 2017 Jul;78(1):215-225. doi: 10.1002/mrm.26370. PMID: 27521026 [doi] [pmid]
7. Gram M, Gensler D, Winter P, Seethaler M, Arias-Loza PA, Oberberger J, Jakob PM, Nordbeck P. Fast myocardial T1ρ mapping in mice using k-space weighted image contrast and a Bloch simulation-optimized radial sampling pattern. MAGMA. 2022 Apr;35(2):325-340. doi: 10.1007/s10334-021-00951-y. PMID: 34491466 [doi] [pmid]
8. Velasco C, Cruz G, Lavin B, Hua A, Fotaki A, Botnar RM, Prieto C. Simultaneous T1, T2, and T1ρ cardiac magnetic resonance fingerprinting for contrast agent-free myocardial tissue characterization. Magn Reson Med. 2022 Apr;87(4):1992-2002. doi: 10.1002/mrm.29091. PMID: 34799854 [doi] [pmid]
9. Kaplan S, da Cruz GL, Madamanchi C, Murthy VL, Swanson S, Hamilton J, Seiberlich N. Simultaneous T1, T2, and T1ρ mapping of the myocardium using cardiac MR fingerprinting with a deep image prior reconstruction. Magn Reson Med. 2025 Oct;94(4):1500-1513. doi: 10.1002/mrm.30580. PMID: 40407793 [doi] [pmid]
10. Layton KJ, Kroboth S, Jia F, Littin S, Yu H, Leupold J, Nielsen JF, Stöcker T, Zaitsev M. Pulseq: A rapid and hardware-independent pulse sequence prototyping framework. Magn Reson Med. 2017 Apr;77(4):1544-1552. doi: 10.1002/mrm.26235. PMID: 27271292 [doi] [pmid]
11. Scholand N, Wang X, Roeloffs V, Rosenzweig S, Uecker M. Quantitative MRI by nonlinear inversion of the Bloch equations. Magn Reson Med. 2023 Aug;90(2):520-538. doi: 10.1002/mrm.29664. PMID: 37093980 [doi] [pmid]
12. Hamilton JI, Jiang Y, Ma D, Chen Y, Lo WC, Griswold M, Seiberlich N. Simultaneous multislice cardiac magnetic resonance fingerprinting using low rank reconstruction. NMR Biomed. 2019 Feb;32(2):e4041. doi: 10.1002/nbm.4041. PMID: 30561779 [doi] [pmid]
13. Stupic KF, Ainslie M, Boss MA, Charles C, Dienstfrey AM, Evelhoch JL, Finn P, Gimbutas Z, Gunter JL, Hill DLG, Jack CR, Jackson EF, Karaulanov T, Keenan KE, Liu G, Martin MN, Prasad PV, Rentz NS, Yuan C, Russek SE. A standard system phantom for magnetic resonance imaging. Magn Reson Med. 2021 Sep;86(3):1194-1211. doi: 10.1002/mrm.28779 [doi]
14. Coletti C, Fotaki A, Tourais J, Zhao Y, van de Steeg-Henzen C, Akçakaya M, Tao Q, Prieto C, Weingärtner S. Robust cardiac T1ρ mapping at 3T using adiabatic spin-lock preparations. Magn Reson Med. 2023 Oct;90(4):1363-1379. doi: 10.1002/mrm.29713. PMID: 37246420 [doi] [pmid]
15. Si D, Crabb MG, Littlewood SJ, Kunze KP, Varghese J, Binzel K, Khan M, Simonetti OP, Prieto C, Botnar RM. Initial experience of cardiac T1ρ mapping at 0.55 T: Continuous wave versus adiabatic spin-lock preparation pulses. Magn Reson Med. 2025 Oct;94(4):1644-1653. doi: 10.1002/mrm.30582. PMID: 40391626 [doi] [pmid]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/401-03-007