Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
662-03-002 ISMRM Abstract

Lumbar Vertebral Marrow PDFF Improves the Diagnostic Specificity for Prostate Cancer: a Preliminary Study

Primary: Body - Prostate
Secondary: Analysis Methods - Classification and Prediction
662-03-002 · Classification: Other Cancer · Thursday, 14 May, 1:40 PM–2:35 PM · Digital Posters Row C
Keywords: Magnetic resonance imaging Proton density fat fraction (PDFF) Prostate cancer Bone marrow fat content
Accepted
Qinglin Xie 1, Xueting Du, Qianyi Qiu, Yi Yang, Xinru Zhang, Yiou Wang1, Jinling wu1, Meimei Zhang, Yuting Ling2, Xiaoyun Liang3, Zhongping Zhang4, Peng Wu4, Ge Wen5, Xiaodong Zhang1
1The Third Affiliated Hospital Southern Medical University, Guangzhou, China
2Institute of Research and Clinical Innovations, Neusoft Medical Systems Co., Ltd, Shanghai, China
3Neusoft Medical Systems Co., Ltd., Hangzhou, China
4Philips Healthcare, Guangzhou, China
5Department of Diagnostic Imaging, Nanfang Hospital, Southern Medical University, Guangzhou, China
Presenting Author: Qinglin Xie

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References

1. [1] Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, et al. Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA Cancer J Clin. 2021 May;71(3):209–49.
2. [2] Chen S, Yang Y, Peng T, Yu X, Deng H, Guo Z. The prediction value of PI-RADS v2 score in high-grade Prostate Cancer: a multicenter retrospective study. Int J Med Sci. 2020 May 30;17(10):1366–74.
3. [3] Oerther B, Nedelcu A, Engel H, Schmucker C, Schwarzer G, Brugger T, et al. Update on PI-RADS Version 2.1 Diagnostic Performance Benchmarks for Prostate MRI: Systematic Review and Meta-Analysis. Radiology. 2024 Aug;312(2):e233337.
4. [4] Luo G, He Y, Yu X. Bone Marrow Adipocyte: An Intimate Partner With Tumor Cells in Bone Metastasis. Front Endocrinol (Lausanne). 2018;9:339.
5. [5] Jackett KN, Browne AT, Aber ER, Clements M, Kaplan RN. How the bone microenvironment shapes the pre-metastatic niche and metastasis. Nat Cancer. 2024 Dec;5(12):1800–14.
6. [6] Proton density fat fraction MRI of vertebral bone marrow: Accuracy, repeatability, and reproducibility among readers, field strengths, and imaging platforms - PubMed [Internet]. [cited 2025 Apr 16]. Available from: https://pubmed.ncbi.nlm.nih.gov/30980694/ [pmid]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/662-03-002