552-01-002 / 552-01-002 ISMRM Abstract

Impact of low-rank denoising on cerebral metabolic flux estimates from dynamic deuterium MRSI at 7T

Primary: Contrast Mechanisms - Deuterium

Secondary: Acquisition & Reconstruction - Spectroscopy and spectroscopic imaging

552-01-002 · Novel Approaches to Spectroscopy · Wednesday, 13 May, 8:20 AM–9:56 AM · Power Pitch Theatre 2

Keywords: Sparse & Low-Rank Models MRSI Deuterium Metabolic Imaging Glucose metabolism Model fitting

Accepted

Anna Duguid ¹, Wolfgang Bogner^1,2, Fabian Niess¹, Lukas Hingerl¹, Viola Bader¹, Sabina Frese¹, Aaron P Osburg¹, Hauke Fischer¹, Martin Krssak³, Ivan Petrović^1,4, Alessio Siviglia^5,6, Brayan Alves^5,6, Cristina Cudalbu^5,6, Bernard Lanz^5,6, Bernhard Strasser¹

¹High Field MR Center, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria

²Christian Doppler Laboratory for MR Imaging Biomarkers (BIOMAK), Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria

³Clinical Division of Internal Medicine III, Department of Endocrinology and Metabolism, Medical University of Vienna, Vienna, Austria

⁴Department of Neurology, Medical University of Vienna, Vienna, Austria

⁵CIBM Center for Biomedical Imaging, EPFL, Lausanne, Switzerland

⁶CIBM Pre-Clinical Imaging EPFL Metabolic Imaging Section, EPFL, Lausanne, Switzerland

Presenting Author: Anna Duguid

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References

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13. Bader V, Strasser B, Bogner W, et al. Concentric Ring Trajectory Sampling With k-Space Reordering Enables Assessment of Tissue-Specific T1 and T2 Relaxation for 2H-Labeled Substrates in the Human Brain at 7 T. NMR Biomed. 2025;38(2):e5311. https://doi.org/10.1002/nbm.5311. [doi]

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http://echo.ismrm.org/p/ISMRM2026/552-01-002