Synopsis
Motivation:
Goals:
Approach:
Results:
551-03-001 / 551-03-001
ISMRM Abstract
Impaired Cerebral Oxygen Metabolism and Cognition in Type-2 Diabetes is Reversed by Novel GIP/GLP-1 Receptor Agonist Therapy
Accepted
Full abstract & presentation
The full text, figures, and any recorded presentation for this abstract are not shown here. Log in if you are a member or registered attendee with access.
Full abstracts, figures, and presentations for Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition are available to registered attendees. This content becomes freely available to the public roughly two years after the meeting.
To request or purchase access, contact the ISMRM Central Office at info@ismrm.org.
Log inReferences
1. Li Y, Liu Y, Liu S, et al. Diabetic vascular diseases: molecular mechanisms and therapeutic strategies. Signal Transduction and Targeted Therapy. 2023/04/10 2023;8(1):152. doi:10.1038/s41392-023-01400-z [doi]
2. Thomas BP, Tarumi T, Sheng M, et al. Brain Perfusion Change in Patients with Mild Cognitive Impairment After 12 Months of Aerobic Exercise Training. J Alzheimers Dis. 2020;75(2):617-631. doi:10.3233/jad-190977 [doi]
3. Alsop DC, Detre JA, Golay X, et al. Recommended implementation of arterial spin-labeled perfusion MRI for clinical applications: A consensus of the ISMRM perfusion study group and the European consortium for ASL in dementia. Magnetic Resonance in Medicine. 2015;73(1):102-116. doi:https://doi.org/10.1002/mrm.25197 [doi]
4. Anwar N, Tucker WJ, Puzziferri N, et al. Cognition and brain oxygen metabolism improves after bariatric surgery-induced weight loss: A pilot study. Article. Frontiers in Endocrinology. 2022;13954127. doi:10.3389/fendo.2022.954127 [doi]
5. Xu F, Ge Y, Lu H. Noninvasive quantification of whole-brain cerebral metabolic rate of oxygen (CMRO2) by MRI. Magnetic Resonance in Medicine. 2009;62(1):141-148. doi:https://doi.org/10.1002/mrm.21994 [doi]
6. Randolph C, Tierney MC, Mohr E, Chase TN. The Repeatable Battery for the Assessment of Neuropsychological Status (RBANS): Preliminary Clinical Validity. Journal of Clinical and Experimental Neuropsychology. 1998/06/01 1998;20(3):310-319. doi:10.1076/jcen.20.3.310.823 [doi]
7. Linari I, Juantorena GE, Ibáñez A, Petroni A, Kamienkowski JE. Unveiling Trail Making Test: visual and manual trajectories indexing multiple executive processes. Scientific Reports. 2022/08/22 2022;12(1):14265. doi:10.1038/s41598-022-16431-9 [doi]
8. Delis DC, Kaplan E, Kramer JH. Delis-Kaplan executive function system. Assessment. 2001;
9. Kaplan E, Goodglass H, Weintraub S. Boston naming test. The Clinical Neuropsychologist. 2001;
10. Li C, Neugroschl J, Luo X, et al. The Utility of the Cognitive Function Instrument (CFI) to Detect Cognitive Decline in Non-Demented Older Adults. J Alzheimers Dis. 2017;60(2):427-437. doi:10.3233/jad-161294 [doi]
11. Lu H, Xu F, Rodrigue KM, et al. Alterations in cerebral metabolic rate and blood supply across the adult lifespan. Cereb Cortex. Jun 2011;21(6):1426-34. doi:10.1093/cercor/bhq224 [doi]
12. Xu F, Liu P, Pascual JM, Xiao G, Huang H, Lu H. Acute effect of glucose on cerebral blood flow, blood oxygenation, and oxidative metabolism. Hum Brain Mapp. Feb 2015;36(2):707-16. doi:10.1002/hbm.22658 [doi]
13. Loughan AR, Braun SE, Lanoye A. Repeatable Battery for the Assessment of Neuropsychological Status (RBANS): preliminary utility in adult neuro-oncology. Neurooncol Pract. Jul 2019;6(4):289-296. doi:10.1093/nop/npy050 [doi]
Cite this abstract
http://echo.ismrm.org/p/ISMRM2026/551-03-001