Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
403-02-009 Registered Abstract

Integrating DCE-MRI and Synthetic MRI Reveals Pathophysiological Subtypes of Synovitis in Knee Osteoarthritis

Primary: Musculoskeletal - Other Musculoskeletal
Secondary: Analysis Methods - Classification and Prediction
403-02-009 · AI-Enabled Image Synthesis and Translation · Tuesday, 12 May, 1:40 PM–3:30 PM · Auditorium 1
Keywords: DCE-MRI Cluster analysis Synthetic MRI Quantitative parameters Synovitis
Accepted
Meng Zhang 1, Weiyin Vivian Liu2, Yong Zhu3, Luanning Li, Xiaokang Wang3, Xuying Chen3
1Xiangyang Hospital of Traditional Chinese Medicine [Xiangyang Institute of Traditional Chinese Medicine], XiangYang, China
2Bayer Healthcare, Wuhan, China
3Xiangyang Traditional Chinese Medicine Hospital, Hubei Province, Xiangyang, China
Presenting Author: Meng Zhang

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References

1. Yoo HJ, Hong SH, Oh HY, Choi JY, Chae HD, Ahn JM, Kang HS. Diagnostic Accuracy of a Fluid-attenuated Inversion-Recovery Sequence with Fat Suppression for Assessment of Peripatellar Synovitis: Preliminary Results and Comparison with Contrast-enhanced MR Imaging. Radiology. 2017 Jun;283(3):769-778. doi: 10.1148/radiol.2016160155. Epub 2016 Oct 24. PMID: 27775897. [doi] [pmid]
2. de Lange-Brokaar BJ, Ioan-Facsinay A, Yusuf E, Visser AW, Kroon HM, Andersen SN, Herb-van Toorn L, van Osch GJ, Zuurmond AM, Stojanovic-Susulic V, Bloem JL, Nelissen RG, Huizinga TW, Kloppenburg M. Degree of synovitis on MRI by comprehensive whole knee semi-quantitative scoring method correlates with histologic and macroscopic features of synovial tissue inflammation in knee osteoarthritis. Osteoarthritis Cartilage. 2014 Oct;22(10):1606-13. doi: 10.1016/j.joca.2013.12.013. Epub 2013 Dec 21. PMID: 24365722. [doi] [pmid]
3. Crema MD, Felson DT, Roemer FW, Niu J, Marra MD, Zhang Y, Lynch JA, El-Khoury GY, Lewis CE, Guermazi A. Peripatellar synovitis: comparison between non-contrast-enhanced and contrast-enhanced MRI and association with pain. The MOST study. Osteoarthritis Cartilage. 2013 Mar;21(3):413-8. doi: 10.1016/j.joca.2012.12.006. Epub 2012 Dec 28. PMID: 23277189; PMCID: PMC3578385. [doi] [pmid]
4. Roux M, Hilbert T, Hussami M, Becce F, Kober T, Omoumi P. MRI T2 mapping of the knee providing synthetic morphologic images: comparison to conventional turbo spin-echo MRI. Radiology 2019;293(3):620–630.
5. Ge Y, Jia Y, Li Y, Dai J, Guan R, Hu S. Synthetic phase-sensitive inversion-recovery vessel for assessing extramural venous invasion in patients with rectal cancer: imaging quality and added value to T2-wighted imaging. Eur Radiol. 2023 Jun;33(6):4148-4157. doi: 10.1007/s00330-022-09344-8. Epub 2022 Dec 14. PMID: 36515715. [doi] [pmid]
6. Wang K, Liu WV, Yang R, Li L, Lu X, Lei H, Jiang J, Zha Y. Super-resolution synthetic MRI using deep learning reconstruction for accurate diagnosis of knee osteoarthritis. Insights Imaging. 2025 Feb 17;16(1):44. doi: 10.1186/s13244-025-01911-zIF: 4.5 Q1 . PMID: 39961957; PMCID: PMC11832993. [doi] [pmid]
7. Roux M, Hilbert T, Hussami M, Becce F, Kober T, Omoumi P. MRI T2 mapping of the knee providing synthetic morphologic images: comparison to conventional turbo spin-echo MRI. Radiology 2019;293(3):620–630.
8. Yi J, Lee YH, Song HT, Suh JS. Double-inversion recovery with synthetic magnetic resonance: a pilot study for assessing synovitis of the knee joint compared to contrast-enhanced magnetic resonance imaging. Eur Radiol. 2019 May;29(5):2573-2580. doi: 10.1007/s00330-018-5800-9. Epub 2018 Nov 28. PMID: 30488107. [doi] [pmid]
9. Kijowski R, Fritz J. Emerging Technology in Musculoskeletal MRI and CT. Radiology. 2023 Jan;306(1):6-19. doi: 10.1148/radiol.220634. Epub 2022 Nov 22. PMID: 36413131. [doi] [pmid]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/403-02-009