Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
664-01-009 ISMRM Abstract

Resting-State BOLD Detects Diaschisis-Related Cerebellar Cerebrovascular Reactivity in Unilateral Cerebrovascular Occlusion

Accepted
Jie Xu 1, Yi Shan1, Bixiao Cui1, Yayan Yin1, Jiayouzheng Li1, Jing Liu1, Boyan Xu2, Jie Lu1
1Department of Radiology and Nuclear Medicine, Xuanwu Hospital, Capital Medical University, Beijing, China
2MR Research, Beijing, China
Presenting Author: Jie Xu

Synopsis

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References

1. Van Niftrik CHB, Sebök M, Germans MR, Halter M, Pokorny T, Stumpo V, Bellomo J, Piccirelli M, Pangalu A, Katan M, et al. Increased risk of recurrent stroke in symptomatic large vessel disease with impaired BOLD cerebrovascular reactivity. Stroke. 2024;55:613–621. https://doi.org/10.1161/STROKEAHA.123.044259 [doi]
2. Baron JC, Bousser MG, Comar D, Castaigne P. "Crossed cerebellar diaschisis" in human supratentorial brain infarction. Trans Am Neurol Assoc. 1981;105:459-461. PMID: 19645126 [pmid]
3. Sebök M, Van Niftrik CHB, Piccirelli M, Bozinov O, Wegener S, Esposito G, Pangalu A, Valavanis A, Buck A, Luft AR, et al. BOLD cerebrovascular reactivity as a novel marker for crossed cerebellar diaschisis. Neurology. 2018 Oct 2;91(14):e1328-e1337. doi: 10.1212/WNL.0000000000006287. [doi]
4. Baron JC. Fifty Years of Deciphering Stroke Pathophysiology. Stroke. 2025 Jul;56(7):1947-1957. doi: 10.1161/STROKEAHA.125.051163. [doi]
5. Liu P, Liu G, Pinho MC, Lin Z, Thomas BP, Rundle M, Park DC, Huang J, Welch BG, Lu H. Cerebrovascular reactivity mapping using resting-state BOLD functional MRI in healthy adults and patients with moyamoya disease. Radiology. 2021;299:419–425. https://doi.org/10.1148/radiol.2021203568 [doi]
6. Liu P, Li Y, Pinho M, Park DC, Welch BG, Lu H. Cerebrovascular reactivity mapping without gas challenges. NeuroImage. 2017;146:320–326. https://doi.org/10.1016/j.neuroimage.2016.11.054 [doi]
7. Sebök M, Van Niftrik CHB, Piccirelli M, Muscas G, Pangalu A, Wegener S, Stippich C, Regli L, Fierstra J. Crossed Cerebellar Diaschisis in Patients With Symptomatic Unilateral Anterior Circulation Stroke Is Associated With Hemodynamic Impairment in the Ipsilateral MCA Territory. J. Magn. Reson. Imaging. 2021;53:1190–1197. https://doi.org/10.1002/jmri.27410 [doi]

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