Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
430-02-001 ISMRM Abstract

Spiral-mpDYCI for high-resolution multi-parametric dynamic contrast imaging

Primary: Contrast Mechanisms - Perfusion
Secondary: Acquisition & Reconstruction - Pulse Sequence Design: Neuro
430-02-001 · Novel Acquisition Strategies and Open-Source Sequences · Tuesday, 12 May, 8:20 AM–10:10 AM · Meeting Room 2.60
Keywords: DSC & DCE Perfusion Brain tumor Spiral acquisition Multiparametric MRI
Accepted
Yang Chen1,2, Nam G Lee3, Ye Tian3, Junzhou Chen 1,4, Jiayu Xiao1, Qingle Kong1, Anthony G Christodoulou5, Debiao Li4, Mark Shiroishi6, Krishna S Nayak2,3, Eric Chang7, Zhaoyang Fan1,2
1Department of Radiology, University of Southern California, Los Angeles, United States of America
2Alfred E. Mann Department of Biomedical Engineering, University of Southern California, Los Angeles, United States of America
3Ming Hsieh Department of Electrical and Computer Engineering, University of Southern California, Los Angeles, United States of America
4Biomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, United States of America
5Department of Radiological Sciences, University of California Los Angeles, Los Angeles, United States of America
6Department of Radiology, Los Angeles General Medical Center, Los Angeles, United States of America
7Department of Radiation Oncology, University of Southern California, Los Angeles, United States of America
Presenting Author: Junzhou Chen

Synopsis

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References

1. Chen Y, Xiao J, Cen S, et al. Multiparametric Dynamic Contrast Imaging for Voxelwise Quantitative Assessment of Brain Tumors. Radiol: Imaging Cancer. 2025;7(5):e250049. doi:10.1148/rycan.250049 [doi]
2. Layton KJ, Kroboth S, Jia F, et al. Pulseq: A rapid and hardware-independent pulse sequence prototyping framework. Magn Reson Med. 2017;77(4):1544-1552. doi:10.1002/mrm.26235 [doi]
3. Ashley G Anderson III, Ryan K Robison, Dinghui Wang, Melvyn B Ooi, James G Pipe. Intra-Scan Center Frequency Drift Correction for 3D Spiral Exams. Proc. Intl. Soc. Mag. Reson. Med. 25; 2017. p1482.
4. Pipe JG, Zwart NR. Spiral trajectory design: A flexible numerical algorithm and base analytical equations. Magn Reson Med. 2014;71(1):278-285. doi:10.1002/mrm.24675 [doi]
5. Hargreaves BA, Nishimura DG, Conolly SM. Time-optimal multidimensional gradient waveform design for rapid imaging. Magn Reson Med. 2004;51(1):81-92. doi:10.1002/mrm.10666 [doi]
6. Brodsky EK, Klaers JL, Samsonov AA, Kijowski R, Block WF. Rapid measurement and correction of phase errors from B0 eddy currents: Impact on image quality for non-cartesian imaging. Magn Reson Med. 2013;69(2):509-515. doi:10.1002/mrm.24264 [doi]
7. Zwart NR, Johnson KO, Pipe JG. Efficient sample density estimation by combining gridding and an optimized kernel. Magn Reson Med. 2012;67(3):701-710. doi:10.1002/mrm.23041 [doi]
8. Sutton BP, Noll DC, Fessler JA. Fast, Iterative Image Reconstruction for MRI in the Presence of Field Inhomogeneities. IEEE Trans Méd Imaging. 2003;22(2):178-188. doi:10.1109/tmi.2002.808360 [doi]
9. Christodoulou AG, Shaw JL, Nguyen C, et al. Magnetic resonance multitasking for motion-resolved quantitative cardiovascular imaging. Nat Biomed Eng. 2018;2(4):215-226. doi:10.1038/s41551-018-0217-y [doi]
10. Paulson ES, Prah DE, Schmainda KM. Spiral Perfusion Imaging With Consecutive Echoes (SPICETM) for the Simultaneous Mapping of DSC- and DCE-MRI Parameters in Brain Tumor Patients: Theory and Initial Feasibility. Tomogr. 2016;2(4):295-307. doi:10.18383/j.tom.2016.00217 [doi]
11. Stokes AM, Ragunathan S, Robison RK, et al. Development of a spiral spin- and gradient-echo (spiral-SAGE) approach for improved multi-parametric dynamic contrast neuroimaging. Magnet Reson Med. 2021;86(6):3082-3095. doi:10.1002/mrm.28933 [doi]
12. Velikina JV, Jung Y, Field AS, Samsonov AA. High-resolution dynamic susceptibility contrast perfusion imaging using higher-order temporal smoothness regularization. Magn Reson Med. 2023;89(1):112-127. doi:10.1002/mrm.29425 [doi]
13. Li Z, Wang D, Ooi MB, et al. A 3D dual-echo spiral sequence for simultaneous dynamic susceptibility contrast and dynamic contrast-enhanced MRI with single bolus injection. Magn Reson Med. 2024;92(2):631-644. doi:10.1002/mrm.30077 [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/430-02-001