Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
605-03-003 ISMRM Abstract

Cerebral blood flow decline in neurodegeneration using a healthy reference normative model

Primary: Neuro - Aging
Secondary: Neuro - Dementia
605-03-003 · Next-Generation Neuroimaging for Alzheimer’s Disease: From Molecules to Networks · Thursday, 14 May, 4:00 PM–5:50 PM · Ballroom West
Keywords: Neurodegeneration Aging Normative modeling Arterial Spin Labelling (ASL) Perfusion MRI
Accepted
Mathijs Dijsselhof 1,2, David R Van Nederpelt2,3, Wibeke Nordhøy4, Ole A Andreassen5,6, Lars T Westlye5,6,7, Luigi Lorenzini1,2,8, Leo Pieperhoff1,2, Alle Meije Wink1,2, Floor Duits9,10,11, Alun D Hughes12, Jonathan M Schott13, Menno Schoonheim14, Eva Strijbis15, Joost Kuijer16,17, Bert-Jan H Van den Born18,19, Mervin Tee20, Saima Hilal20,21,22, Christopher Chen21,22, Frederik Barkhof1,2,23, James H Cole24, Jan Petr1,25, Henk J Mutsaerts1,2
1Radiology and Nuclear Medicine, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, Netherlands
2Brain Imaging, Amsterdam Neuroscience, Amsterdam, Netherlands
3Radiology & Nuclear Medicine, MS Center Amsterdam, Amsterdam, Netherlands
4Department for Physics and Computational Radiology, Oslo University Hospital, Oslo, Norway
5Precision Psychiatry, Oslo University Hospital, Oslo, Norway
6Psychology, Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway
7KG Jebsen Centre for Neurodevelopmental Disorders, Norway
8Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genoa, Genoa, Italy
9Alzheimer Center Amsterdam, Netherlands
10Neurodegeneration, Amsterdam Neuroscience, Amsterdam, Netherlands
11Neurochemistry lab, Amsterdam Neuroscience, Amsterdam, Netherlands
12MRC Unit for Lifelong Health & Ageing, University College London, London, United Kingdom
13Dementia Research Centre, UCL Queen Square Institute of Neurology, London, United Kingdom
14Anatomy and Neurosciences, MS Center Amsterdam, Amsterdam, Netherlands
15Neurology, MS Center Amsterdam, Amsterdam, Netherlands
16Department of Radiology & Nuclear Medicine, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, Netherlands
17Amsterdam Neuroscience, Brain Imaging, MS Center Amsterdam, Amsterdam, Netherlands
18Internal Medicine, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, Netherlands
19Public and Occupational health, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, Netherlands
20Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore
21Pharmacology, National University of Singapore, Singapore, Singapore
22Memory Aging and Cognition Centre, National University Health System (NUHS), Singapore, Singapore
23Queen Square Institute of Neurology, University College London, London, United Kingdom
24University College London, London, United Kingdom
25Helmholtz-Zentrum Dresden Rossendorf, Germany
Presenting Author: Mathijs Dijsselhof

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References

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http://echo.ismrm.org/p/ISMRM2026/605-03-003