Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
570-05-201 ISMRM Abstract

BAT activation rewires systemic and tumor glucose metabolism revealed by deuterium metabolic imaging

Primary: Contrast Mechanisms - Deuterium
Secondary: Preclinical Animal & in vitro MR - Small Animals
570-05-201 · MRI of Brown Adipose Tissue: Feel the Heat · Wednesday, 13 May, 1:40 PM–2:35 PM · Traditional Posters | Exhibition Hall
Keywords: Deuterium Metabolic Imaging Glucose metabolism Brown adipose tissue Deuterium-labeled glucose Noninvasive metabolic imaging
Accepted
Shangpo Yang1, Ganghan Yang2,3, Qian Wan3, Wenming Deng4, Yijia Zheng1, Cuien Zheng5, Siyi Wu6, Dehong Luo1, Chao Zou3,7,8, Zhou Liu 4
1Department of Radiology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
2The School of Electronics and Information Engineering, Harbin Institute of Technology, HARBIN, China
3Paul C. Lauterbur Research Center for Biomedical Imaging, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China
4National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
5Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China
6Research Center for Medical AI, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China
7State Key Laboratory of Biomedical Imaging Science and System, Shenzhen, China
8Key Laboratory for Magnetic Resonance and Multimodality Imaging of Guangdong Province, Shenzhen, China
Presenting Author: Zhou Liu

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References

1. Vander Heiden MG, Cantley LC, Thompson CB. Understanding the Warburg effect: the metabolic requirements of cell proliferation. Science (New York, NY). May 22 2009;324(5930):1029-33. doi:10.1126/science.1160809 [doi]
2. Seki T, Yang Y, Sun X, et al. Brown-fat-mediated tumour suppression by cold-altered global metabolism. Nature. Aug 2022;608(7922):421-428. doi:10.1038/s41586-022-05030-3 [doi]
3. Hankir MK, Klingenspor M. Brown adipocyte glucose metabolism: a heated subject. EMBO reports. Sep 2018;19(9)doi:10.15252/embr.201846404 [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/570-05-201