Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
608-03-007 ISMRM Abstract

Whole-Brain Mapping of Formaldehyde Fixation Using Multiparametric MRI

Primary: Contrast Mechanisms - Multi-Contrast
Secondary: Contrast Mechanisms - Relaxometry
608-03-007 · Quantitative Imaging: Multiparametric and Synthetic MRI · Thursday, 14 May, 4:00 PM–5:50 PM · Meeting Room 1.60
Keywords: Ex-Vivo Applications Diffusion MRI T2 relaxometry Fixation T1 relaxation time
Accepted
Chenyang Li1, Huize Pang1, Tianyu Gao1, Rohit Jena2, Dominique Leitner3, Thomas Wisniewski4,5,6, Arline Faustin6,7, Henrieta Scholtzova3, Laura Gould3, Orrin Devinsky3, James Gee2, Youssef Z Wadghiri1, Jiangyang Zhang1, Yulin Ge 1
1Department of Radiology, NYU Grossman School of Medicine, New York, United States of America
2University of Pennsylvania, Philadelphia, United States of America
3Department of Neurology, NYU Grossman School of Medicine, New York, United States of America
4Neurology, NYU Grossman School of Medicine, New York, United States of America
5Department of Psychiatry, NYU Grossman School of Medicine, New York, United States of America
6Department of Pathology, NYU Grossman School of Medicine, New York, United States of America
7pathology, NYU Grossman School of Medicine, New York, United States of America
Presenting Author: Yulin Ge

Synopsis

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References

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8. Shatil AS, Uddin MN, Matsuda KM, Figley CR. Quantitative Ex Vivo MRI Changes due to Progressive Formalin Fixation in Whole Human Brain Specimens: Longitudinal Characterization of Diffusion, Relaxometry, and Myelin Water Fraction Measurements at 3T. Front Med (Lausanne) 2018;5:31.
9. Raman MR, Shu Y, Lesnick TG, Jack CR, Kantarci K. Regional T(1) relaxation time constants in Ex vivo human brain: Longitudinal effects of formalin exposure. Magn Reson Med 2017;77(2):774-778.
10. Miller KL, Stagg CJ, Douaud G, Jbabdi S, Smith SM, Behrens TEJ, Jenkinson M, Chance SA, Esiri MM, Voets NL, Jenkinson N, Aziz TZ, Turner MR, Johansen-Berg H, McNab JA. Diffusion imaging of whole, post-mortem human brains on a clinical MRI scanner. Neuroimage 2011;57(1):167-181.
11. Roebroeck A, Miller KL, Aggarwal M. Ex vivo diffusion MRI of the human brain: Technical challenges and recent advances. NMR Biomed 2019;32(4):e3941.

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/608-03-007