366-04-001 ISMRM Abstract

Hyperpolarized ¹³C‑Pyruvate MRI Detects Early Metabolic Transition from Healthy Liver to MASH and to HCC

Primary: Preclinical Animal & in vitro MR - Probes & Targets

Secondary: Contrast Mechanisms - Hyperpolarized MR (Non-Gas)

366-04-001 · Probes and Targets · Monday, 11 May, 2:45 PM–3:40 PM · Digital Posters Row G

Keywords: Hepatocellular carcinoma Hyperpolarized 13C MRI Metabolic Dysfunction-Associated Steatohepatitis Dynamic nuclear polarization Parahydrogen-induced hyperpolarization

Accepted

Mohammad Ghaderian^1,2,3, Vera Jörke^1,2, Theresa Hune^4,5, Oliver Hihn^1,2,3, Anais Choffart^1,2,3, Laimdota Zizmare¹, Sergey Korchak^4,5, Max Zimmermann^1,2,3, Lisa Fries^4,5, Gyuantae Bae^1,2, Irene Gonzalez-Menendez⁶, Leticia Quintanilla-Martinez⁶, Nicolas Kempf^4,5, Kai Buckenmaier^4,5, Stefan Glöggler^5,7, Johannes Schwenck^1,2,8, Andre F Martins^1,2,3

¹Werner Siemens Imaging Center, Department of Preclinical Imaging and Radiopharmacy, Germany

²Cluster of Excellence iFIT (EXC 2180) "Image-Guided and Functionally Instructed Tumor Therapies," University of Tübingen, Tuebingen, Germany

³German Cancer Consortium (DKTK), partner site Tübingen, German Cancer Research Center (DKFZ), Heidelberg, Germany

⁴Center for Biostructural Imaging of Neurodegeneration of UMG, NMR Signal Enhancement Group, Göttingen, Germany

⁵NMR Signal Enhancement Group, Max Planck Institute for Multidisciplinary Sciences, Goettingen, Germany

⁶Institute of Pathology and Neuropathology, Comprehensive Cancer Center, Eberhard Karls University, Tübingen, Germany

⁷University of Texas Southwestern Medical Center, Dallas, United States of America

⁸Eberhard Karls University Tübingen, Tübingen, Germany

Presenting Author: Remy Chiaffarelli

Synopsis

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References

1. 10.7150/thno.103272 [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/366-04-001