Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
669-01-001 ISMRM Abstract

Assessing heterogeneity of Multiple Sclerosis lesions by APTw CEST MRI: Insights into lesion biology

Primary: Contrast Mechanisms - CEST / APT / NOE
Secondary: Neuro - Multiple Sclerosis
669-01-001 · Neuroinflammation: Metabolites, Function, and AI · Thursday, 14 May, 8:30 AM–9:25 AM · Digital Posters Row J
Keywords: Multiple Sclerosis Neuroinflammation Heterogeneity CEST MRI APTw-CEST
Accepted
Evgeny Golubtsov1, Nico Sollmann2,3,4,5,6,7,8, Isabelle Schmid4, Noah Enbergs1, Julius M Kernbach1, Strahinja Stojanovic9, Daniel Schwarz1, Meinrad Beer10, Johannes Rosskopf4, Deborah Erhart4, Stefanie Jung4, Patrick Liebig11,12,13,14,15,16,17,18, Hayrettin Tumani4, Laura Jäger19, Klemens Ruprecht19, Wolfgang Wick20, Daniel Paech21,22,23, Sabine Heiland9, Martin Bendszus9, Michael O Breckwoldt1, Kianush Karimian-Jazi 1
1Department of Neuroradiology, University Hospital Heidelberg, Heidelberg, Germany
2Department of Diagnostic and Interventional Neuroradiology, TUM University Hospital, Munich, Germany
3TUM-Neuroimaging Center, TUM University Hospital, Munich, Germany
4Department of Diagnostic and Interventional Radiology, University Hospital Ulm, Ulm, Germany
5University Hospital Ulm, Ulm, Germany
6Department of Nuclear Medicine, University Hospital Ulm, Ulm, Germany
7Institute for Diagnostic and Interventional Neuroradiology, Technical University of Munich, School of Medicine and Health, Munich, Germany
8TUM-NIC Neuroimaging Center, Technical University of Munich, School of Medicine and Health, Munich, Germany
9Department of Neuroradiology, Heidelberg University Hospital, Heidelberg, Germany
10Department for Diagnostic and Interventional Radiology, Ulm University, Medical Center, Ulm, Germany
11Siemens Healthineers AG, Erlangen, Germany
12MR Application Predevelopment, Siemens Healthineers, Erlangen, Germany
13Siemens Healthineers AG, Forchheim, Germany
14MR Application Predevelopment, Siemens Healthineers AG, Forchheim, Germany
15Siemens Healthineers GmbH, Forchheim, Germany
16MR Application Development, Siemens Healthineers AG, Erlangen, Germany
17Siemens Healthineers GmbH, Forchheim, Germany
18MR Advanced Systems, Siemens Healthineers AG, Erlangen, Germany
19Department of Neurology, University Hospital Heidelberg, Heidelberg, Germany
20Department of Neurology, Heidelberg University Hospital, Heidelberg, Germany
21Mass General Brigham, Somerville, United States of America
22Department of Radiology, Brigham and Women's Hospital and Harvard Medical School, Boston, United States of America
23Division of Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany
Presenting Author: Kianush Karimian-Jazi

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http://echo.ismrm.org/p/ISMRM2026/669-01-001