Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
469-03-013 ISMRM Abstract

Neurometabolic Changes in Traumatic Brain Injury patients: Establishing and Enabling 1H-MRS Data Acquisition and Analysis

Accepted
Siddharth S Singh1, Saipavitra Murali-Manohar2, Maninder Singh1, BV Rathish Kumar3, Sudhir K Pathak4, Ekta Dixit1, Anit Parihar1, Anil Chandra5, Manoj Kumar1, Bal K Ojha5, Durgesh K Dwivedi 1
1Radiodiagnosis, King George's Medical University, Lucknow, India
2The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, United States of America
3Department of Mathematics and Statistics, Indian Institute of Technology, Kanpur, India
4Learning Research and Development Center, University of Pittsburgh, Pittsburgh, United States of America
5Neurosurgery, King George's Medical University, Lucknow, India
Presenting Author: Durgesh K Dwivedi

Synopsis

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References

1. Bartnik-Olson, B. L., Alger, J. R., Babikian, T., Harris, A. D., Holshouser, B., Kirov, I. I., ... & Lin, A. (2021). The clinical utility of proton magnetic resonance spectroscopy in traumatic brain injury: recommendations from the ENIGMA MRS working group. Brain imaging and behavior, 15(2), 504-525. DOI: https://doi.org/10.1007/s11682-020-00330-6 [doi]
2. Joyce JM, La PL, Walker R, Harris AD. Magnetic Resonance Spectroscopy of Traumatic Brain Injury and Subconcussive Hits: A Systematic Review and Meta-Analysis. J Neurotrauma. 2022 Nov;39(21-22):1455-1476. DOI: https://doi.org/10.1089/neu.2022.0125 [doi]
3. Hui, S. C., Saleh, M. G., Zöllner, H. J., Oeltzschner, G., Fan, H., Li, Y., ... & Edden, R. A. (2022). MRSCloud: A cloud‐based MRS tool for basis set simulation. Magnetic resonance in medicine, 88(5), 1994-2004. DOI:https://doi.org/10.1002/mrm.29370 [doi]
4. Oeltzschner G, Zöllner HJ, Hui SC et al.. Osprey: Open-source processing, reconstruction & estimation of magnetic resonance spectroscopy data. Journal of neuroscience methods. 2020;343:108827. DOI:https://doi.org/10.1016/j.jneumeth.2020.108827 [doi]
5. Zöllner HJ, Davies-Jenkins CW, Lee EG et al. Continuous automated analysis workflow for MRS studies. Journal of medical systems. 2023;47(1):69. DOI:https://doi.org/10.1016/j.jneumeth.2020.108827 [doi]
6. Near J, Harris AD, Juchem C et al. Preprocessing, analysis and quantification in single‐voxel magnetic resonance spectroscopy: experts' consensus recommendations. NMR in Biomedicine. 2021;34(5):e4257. DOI: https://doi.org/10.1002/nbm.4257 [doi]
7. Wilson M, Andronesi O, Barker PB et al. Methodological consensus on clinical proton MRS of the brain: Review and recommendations. Magnetic resonance in medicine. 2019;82(2):527-50. DOI: https://doi.org/10.1002/mrm.27742 [doi]
8. Joyce, Julie M., Parker L. La, Robyn Walker, and Ashley D. Harris. "Magnetic resonance spectroscopy of traumatic brain injury and subconcussive hits: A systematic review and meta–analysis." Journal of Neurotrauma 39, no. 21-22 (2022): 1455-1476. DOI:10.1089/neu.2022.0125 [doi]

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