366-06-004 ISMRM Abstract

Fasciculation volume measured with stimulated echo diffusion-weighted MRI correlates with muscle weakness in older adults

Primary: Musculoskeletal - Muscle

Secondary: Diffusion - Diffusion Analysis & Visualization

366-06-004 · Body Diffusion MRI Applications · Monday, 11 May, 5:05 PM–6:00 PM · Digital Posters Row G

Keywords: Muscle Force Musculoskeletal MRI Diffusion-Weighted Imaging Time-dependent diffusion MRI MUSCLE AGING

Accepted

Gabrielle Baxter ^1,2, Santiago Coelho^1,2, Smita Rao³, Thorsten Feiweier⁴, Els Fieremans^1,2, Valentina Mazzoli^1,2

¹Department of Radiology, Center for Advanced Imaging Innovation and Research (CAI²R), New York University Grossman School of Medicine, New York, United States of America

²Department of Radiology, New York University Grossman School of Medicine, New York, United States of America

³New York University, New York, United States of America

⁴MR Research & Clinical Translation, Erlangen, Germany

Presenting Author: Gabrielle Baxter

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References

1. Heskamp L, Birkbeck MG, Baxter-Beard D, Hall J, Schofield IS, Elameer M, Whittaker RG, Blamire AM. Motor Unit Magnetic Resonance Imaging (MUMRI) In Skeletal Muscle. J Magn Reson Imaging. 2024 Dec;60(6):2253-2271 doi: 10.1002/jmri.29218. [doi]

2. Sayer AA, Robinson SM, Patel HP, Shavlakadze T, Cooper C, Grounds MD. New horizons in the pathogenesis, diagnosis and management of sarcopenia. Age Ageing. 2013 Mar;42(2):145-50. doi: 10.1093/ageing/afs191. [doi]

3. Schwartz M, Steidle G, Martirosian P, et al. Estimation of the sensitivity characteristics and detection capability of diffusion-weighted MR sequences in imaging spontaneous mechanical activity in musculature. Int Soc Magn Reson Med 2017; 5005.

4. McKay MJ, Weber KA II, Wesselink EO, Smith ZA, Abbott R, Anderson DB, Ashton-James CE, Atyeo J, Beach AJ, Burns J, et al. MuscleMap: An Open-Source, Community-Supported Consortium for Whole-Body Quantitative MRI of Muscle. Journal of Imaging. 2024; 10(11):262. doi: 10.3390/jimaging10110262. [doi]

5. Piasecki, M., Ireland, A., Jones, D. A., & McPhee, J. S. (2016). Age-dependent motor unit remodelling in human limb muscles. Biogerontology, 17(3), 485-496. doi: 10.1007/s10522-015-9627-3. [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/366-06-004