Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
465-06-005 ISMRM Abstract

Optimized gradient waveforms for isotropic diffusion and restriction weighting via double-isotropic matched encoding (DIME)

Primary: Diffusion - Diffusion Acquisition
Secondary: Diffusion - Microstructure
465-06-005 · Diffusion Acquisition · Tuesday, 12 May, 4:55 PM–5:50 PM · Digital Posters Row F
Keywords: Microstructure Concomitant fields Time-dependent diffusion MRI Peripheral Nerve Stimulation Experimental design
Accepted
Felix Mortensen 1, Viktor Olsson1, Athanasios Grigoriou2, Malwina Molendowska1, Samo Lasic3, Filip Szczepankiewicz1
1Department of Medical Radiation Physics, Lund University, Lund, Sweden
2Vall d'Hebron Institute of Oncology, Barcelona, Spain
3Department of Diagnostic Radiology, Lund University, Lund, Sweden
Presenting Author: Felix Mortensen

Synopsis

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References

1. Thomas M. de Swiet and Partha P. Mitra. “Possible Systematic Errors in Single-Shot Measurements of the Trace of the Diffusion Tensor”. In: Journal of Magnetic Resonance, Series B 111.1 (Apr. 1996), pp. 15–22. issn: 1064-1866. doi: 10.1006/jmrb.1996.0055. [doi]
2. Sune Nørhøj Jespersen et al. “Effects of nongaussian diffusion on “isotropic diffusion” measurements: An ex-vivo microimaging and simulation study”. In: Journal of Magnetic Resonance 300 (Mar. 2019), pp. 84–94. issn: 1090-7807. doi: 10.1016/j.jmr.2019.01.007. [doi]
3. Samo Lasič et al. “Spectral Principal Axis System (SPAS) and tuning of tensor-valued encoding for microscopic anisotropy and time-dependent diffusion in the rat brain”. In: Imaging Neuroscience (May 2025). issn: 2837-6056. doi: 10.1162/IMAG.a.35. [doi]
4. H. Lundell et al. “Multidimensional diffusion MRI with spectrally modulated gradients reveals un-precedented microstructural detail”. en. In: Scientific Reports 9.1 (June 2019). Publisher: Nature Publishing Group, p. 9026. issn: 2045-2322. doi: 10.1038/s41598-019-45235-7. [doi]
5. Carl-Fredrik Westin et al. “Q-space trajectory imaging for multidimensional diffusion MRI of the human brain”. eng. In: NeuroImage 135 (July 2016), pp. 345–362. issn: 1095-9572. doi: 10.1016/j.neuroimage.2016.02.039. [doi]
6. Markus Nilsson et al. “Resolution limit of cylinder diameter estimation by diffusion MRI: The impact of gradient waveform and orientation dispersion”. In: Nmr in Biomedicine 30.7 (July 2017), e3711. issn: 0952-3480. doi: 10.1002/nbm.3711. [doi]
7. Henrik Lundell and Samo Lasic. “Chapter 2. Diffusion Encoding with General Gradient Waveforms”. en. In: New Developments in NMR. Ed. by Daniel Topgaard. Cambridge: Royal Society of Chemistry, 2020, pp. 12–67. isbn: 978-1-78801-726-8. doi: 10.1039/9781788019910-00012. [doi]
8. S. Mori and P. C. van Zijl. “Diffusion weighting by the trace of the diffusion tensor within a single scan”. eng. In: Magnetic Resonance in Medicine 33.1 (Jan. 1995), pp. 41–52. issn: 0740-3194. doi:10.1002/mrm.1910330107. [doi]
9. Filip Szczepankiewicz, Carl-Fredrik Westin, and Markus Nilsson. “Gradient waveform design for tensor-valued encoding in diffusion MRI”. In: Journal of Neuroscience Methods 348 (Jan. 2021), p. 109007. issn: 0165-0270. doi: 10.1016/j.jneumeth.2020.109007. [doi]
10. Filip Szczepankiewicz, Carl-Fredrik Westin, and Markus Nilsson. “Maxwell-compensated design of asymmetric gradient waveforms for tensor-valued diffusion encoding”. en. In: Magnetic Resonance in Medicine 82.4 (2019). _eprint: https://onlinelibrary.wiley.com/doi/pdf/10.1002/mrm.27828, pp. 1424–1437. issn: 1522-2594. doi: 10.1002/mrm.27828. [doi]
11. Filip Szczepankiewicz. filip-szczepankiewicz/safe_pns_prediction. original-date: 2018-12-11T18:34:26Z.Oct. 2025
12. Franz X. Hebrank, Matthias Gebhardt M. “SAFE model—a new method for predicting peripheral nerve stimulation in MRI”. In: Proceedings of the International Society for Magnetic Resonance in Medicine, vol. 8, 2000. p. 2007.
13. Jens Sjölund et al. “Constrained optimization of gradient waveforms for generalized diffusion encoding”. In: Journal of Magnetic Resonance 261 (Dec. 2015), pp. 157–168. issn: 1090-7807. doi:10.1016/j.jmr.2015.10.012. [doi]
14. Eric C. Wong, Robert W. Cox, and Allen W. Song. “Optimized isotropic diffusion weighting”. en. In: Magnetic Resonance in Medicine 34.2 (1995). _eprint: https://onlinelibrary.wiley.com/doi/pdf/10.1002/mrm.191034 pp. 139–143. issn: 1522-2594. doi: 10.1002/mrm.1910340202. [doi]
15. Athanasios Grigoriou et al. “Histology-informed microstructural diffusion simulations for MRI cancer characterisation — the Histo-Sim framework”. en. Pages: 2024.07.15.24310280. Dec. 2024. doi: 10.1101/2024.07.15.24310280. [doi]

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http://echo.ismrm.org/p/ISMRM2026/465-06-005