Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
462-04-004 ISMRM Abstract

Multi-parametric qMRI of Quadriceps Muscle to Characterize Osteoarthritis in a Post-Traumatic OA Mice Model

Primary: Preclinical Animal & in vitro MR - Biomarkers
Secondary: Musculoskeletal - Osteoarthritis
462-04-004 · Body, Cardiovascular, and Musculoskeletal Systems in Small Animals · Tuesday, 12 May, 2:35 PM–3:30 PM · Digital Posters Row C
Keywords: Muscle UTE-MT Animal mouse model Diffusion Tensor Imaging (DTI) Post-traumatic osteoarthritis
Accepted
Shantanu Sinha 1, Sheronda Statum1, Sophia Dwek1, Kevin Burt2, Yajun Ma1, Aurea M Borges1, Carla Scanzello3, Usha Sinha4, Christine Chung1
1University of California, Berkeley, United States of America
2University of Pennsylvania, Philadelphia, United States of America
3Corporal Michael J Crescenz VA Medical Center, Philadelphia, United States of America
4San Diego State University, San Diego, United States of America
Presenting Author: Shantanu Sinha

Synopsis

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References

1. Cameron KL, Hsiao MS, Owens BD, Burks R, Svoboda SJ. Incidence of physician-diagnosed osteoarthritis among active-duty United States military service members. Arthritis Rheum. 2011;63(10):2974-2982. doi:10.1002/art.30498. [doi]
2. Cho Y, Jeong S, Kim H, et al. Disease-modifying therapeutic strategies in osteoarthritis: current status and future directions. Exp Mol Med. 2021;53(11):1689-1696. doi:10.1038/s12276-021-00710-y. [doi]
3. Alnahdi AH, Zeni JA, Snyder-Mackler L. Muscle Impairments in Patients With Knee Osteoarthritis. Sports Health. 2012;4(4):284-292. doi:10.1177/1941738112445726. [doi]
4. Shang X, Hao X, Hou W, et al. Exercise-induced modulation of myokine irisin on muscle-bone unit in the rat model of post-traumatic osteoarthritis. J Orthop Surg Res. 2024;19(1). doi:10.1186/s13018 [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/462-04-004