Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
365-03-015 ISMRM Abstract

Definition of a liver function index using intra-voxel incoherent motion modelling for function-guided liver cancer radiation

Primary: Interventional - MR-Guided Radiotherapy
Secondary: Diffusion - IVIM
365-03-015 · Body Diffusion MRI Methods · Monday, 11 May, 1:50 PM–2:45 PM · Digital Posters Row F
Keywords: Modelling Radiotherapy IVIM Quantitative MRI Liver MRI
Accepted
Fidel Navarro Salazar 1, Yu Sun1, Tim Wang2, Sheryl L Foster3,4, Naeim Sanaei3, Jonathan Sykes2, Annette Haworth1,2, Sirisha Tadimalla1,2
1Institute of Medical Physics, The University of Sydney, Sydney, Australia
2Radiation Oncology Network, Western Sydney Local Health District, Sydney, Australia
3Department of Radiology, Westmead Hospital, Sydney, Australia
4Sydney School of Health Sciences, Faculty of Medicine and Health, The University of Sydney, Sydney, Australia
Presenting Author: Fidel Navarro Salazar

Synopsis

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References

1. Pan CC, Kavanagh BD, Dawson LA, et al. Radiation-Associated Liver Injury. International Journal of Radiation Oncology*Biology*Physics. 2010;76(3, Supplement):S94-S100. doi:10.1016/j.ijrobp.2009.06.092 [doi]
2. Brewster F, Middleton Z, McWilliam A, Brocklehurst A, Radhakrishna G, Chuter R. Feasibility of using contrast-free quantitative magnetic resonance imaging for liver sparing stereotactic ablative body radiotherapy. Clinical and Translational Radiation Oncology. 2024;49:100859. doi:10.1016/j.ctro.2024.100859 [doi]
3. Tadimalla S, Wang W, Haworth A. Role of Functional MRI in Liver SBRT: Current Use and Future Directions. Cancers (Basel). 2022;14(23):5860. doi:10.3390/cancers14235860 [doi]
4. Koh DM, Collins DJ, Orton MR. Intravoxel incoherent motion in body diffusion-weighted MRI: reality and challenges. AJR Am J Roentgenol. 2011;196(6):1351-1361. doi:10.2214/AJR.10.5515 [doi]
5. Luciani A, Vignaud A, Cavet M, et al. Liver cirrhosis: intravoxel incoherent motion MR imaging--pilot study. Radiology. 2008;249(3):891-899. doi:10.1148/radiol.2493080080 [doi]
6. Woo S, Lee JM, Yoon JH, Joo I, Han JK, Choi BI. Intravoxel incoherent motion diffusion-weighted MR imaging of hepatocellular carcinoma: correlation with enhancement degree and histologic grade. Radiology. 2014;270(3):758-767. doi:10.1148/radiol.13130444 [doi]
7. fnav0118/IVIM-SE: Main repository for IVIM-SE model. GitHub. https://github.sydney.edu.au/fnav0118/IVIM-SE
8. D’Antonoli TA, Berger LK, Indrakanti AK, et al. TotalSegmentator MRI: Sequence-Independent Segmentation of 59 Anatomical Structures in MR images. arXiv. Preprint posted online May 29, 2024. doi:10.48550/arXiv.2405.19492 [doi]
9. Horn PS, Pesce AJ. Reference intervals: an update. Clinica Chimica Acta. 2003;334(1):5-23. doi:10.1016/S0009-8981(03)00133-5 [doi]

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http://echo.ismrm.org/p/ISMRM2026/365-03-015