271-01-010 / 503-01-003 ISMRM Abstract

Permeability changes measured by dynamic contrast enhancement and revascularization surgery in patients with moyamoya disease

Primary: Neuro - Stroke and Cerebrovascular Disorders

Secondary: Neuro - Neuroinflammation

271-01-010 · ISMRM AMPC Selected Posters · Sunday, 10 May, 7:00 AM–2:00 PM · Traditional Posters

503-01-003 · Innovative Methods To Understand Stroke · Wednesday, 13 May, 8:20 AM–10:10 AM · Auditorium 1

Keywords: Moyamoya disease Dynamic contrast enhancement Blood brain barrier Hemodynamic disturbance Cerebral blood flow

Accepted

Shoko Hara ^1,2, Misaki Miyasaka¹, Yosuke Ishii¹, Shihori Hayashi^1,2, Motoki Inaji^1,2, Kenji Ishii², Yoji Tanaka¹, Taketoshi Maehara¹

¹Neurosurgery, Institute of Science Tokyo, Tokyo, Japan

²Research Team for Neuroimaging, Tokyo Metropolitan Institute of Gerontology, Tokyo, Japan

Presenting Author: Shoko Hara

Synopsis

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References

1. Choi HS, Ahn SS, Shin NY, et al. Permeability Parameters Measured with Dynamic Contrast-Enhanced MRI: Correlation with the Extravasation of Evans Blue in a Rat Model of Transient Cerebral Ischemia. Korean J Radiol 2015; 16: 791-797. 2015/07/16. DOI: 10.3348/kjr.2015.16.4.791. [doi]

2. Kim ES, Lee SK, Kwon MJ, et al. Assessment of Blood-Brain Barrier Permeability by Dynamic Contrast-Enhanced MRI in Transient Middle Cerebral Artery Occlusion Model after Localized Brain Cooling in Rats. Korean J Radiol 2016; 17: 715-724. 20160823. DOI: 10.3348/kjr.2016.17.5.715. [doi]

3. Lee K, Yoo RE, Cho WS, et al. Blood-brain barrier disruption imaging in postoperative cerebral hyperperfusion syndrome using DCE-MRI. J Cereb Blood Flow Metab 2024; 44: 345-354. 20231101. DOI: 10.1177/0271678x231212173. [doi]

4. Lu X, Huang Y, Zhou P, et al. Decreased cortical perfusion in areas with blood-brain barrier dysfunction in Moyamoya disease. Acta Neurochir (Wien) 2020; 162: 2565-2572. 20200722. DOI: 10.1007/s00701-020-04480-w. [doi]

5. Serlin Y, Ofer J, Ben-Arie G, et al. Blood-Brain Barrier Leakage: A New Biomarker in Transient Ischemic Attacks. Stroke 2019; 50: 1266-1269. 2019/04/23. DOI: 10.1161/STROKEAHA.119.025247. [doi]

6. Villringer K, Sanz Cuesta BE, Ostwaldt AC, et al. DCE-MRI blood-brain barrier assessment in acute ischemic stroke. Neurology 2017; 88: 433-440. 2016/12/30. DOI: 10.1212/wnl.0000000000003566. [doi]

7. Tofts PS, Brix G, Buckley DL, et al. Estimating kinetic parameters from dynamic contrast-enhanced T(1)-weighted MRI of a diffusable tracer: standardized quantities and symbols. J Magn Reson Imaging 1999; 10: 223-232. 1999/10/03.

8. Hara S, Kudo T, Hayashi S, et al. Improvement in cognitive decline after indirect bypass surgery in adult moyamoya disease: implication of (15)O-gas positron emission tomography. Annals of nuclear medicine 2020; 34: 467-475. 2020/05/08. DOI: 10.1007/s12149-020-01473-8. [doi]

9. Ogasawara K, Takahashi T, Igarashi S, et al. Effect of the addition of (123)I-iomazenil single-photon emission computed tomography to brain perfusion single-photon emission computed tomography on the detection accuracy of misery perfusion in adult patients with ischemic moyamoya disease. Annals of nuclear medicine 2023 20230218. DOI: 10.1007/s12149-023-01825-0. [doi]

10. Barisano G, Montagne A, Kisler K, et al. Blood-brain barrier link to human cognitive impairment and Alzheimer's Disease. Nat Cardiovasc Res 2022; 1: 108-115. 20220207. DOI: 10.1038/s44161-021-00014-4. [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/271-01-010