131-01-033 ISMRT Abstract

Inverse association between corpus callosum thickness and disability in individuals with multiple sclerosis

131-01-033 · Lunch, Exhibition & Poster Tour · Saturday, 9 May, 12:30 PM–2:00 PM · Roof Terrace

Keywords: Corpus Callosum EDSS Multiple Sclerosis CCI.

Accepted

MARIAAN JAFTHA ¹, Susan J Van Rensburg², Clint Johannes³, Merlisa C Kemp⁴, Penelope Engel-Hills⁵, Ronald Van Toorn², Maritha J Kotze²

¹Cape Universities Body Imaging Centre (CUBIC), University of Cape Town, Cape Town, South Africa

²Stellenbosch University, Stellenbosch, South Africa

³Stellenbosch University and Tygerberg Hospital, Cape Town, South Africa

⁴The University of Exeter, Exeter, United Kingdom

⁵Cape Peninsula University of Technology, Cape Town, South Africa

Presenting Author: MARIAAN JAFTHA

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References

1. 1. Fujimori, J., Uryu, K., Fujihara, K., Wattjes, M.P., Suzuki, C. & Nakashima, I. 2020. Measurements of the corpus callosum index and fractional anisotropy of the corpus callosum and their cutoff values are useful to assess global brain volume loss in multiple sclerosis. Multiple Sclerosis and Related Disorders, 45. 2. Garg, N., Reddel, S.W., Miller, D.H., Chataway, J., Riminton, D.S., Barnett, Y., Masters, L., Barnett, M.H. & Hardy, T.A. 2015. The corpus callosum in the diagnosis of multiple sclerosis and other CNS demyelinating and inflammatory diseases. Journal of Neurology, Neurosurgery and Psychiatry, 86(12): 1374–1382. 3. Gonçalves, L.I., dos Passos, G.R., Conzatti, L.P., Burger, J.L.P., Tomasi, G.H., Zandoná, M.É., Azambuja, L.S., Gomes, I., Franco, A., Sato, D.K. & Becker, J. 2018. Correlation between the corpus callosum index and brain atrophy, lesion load, and cognitive dysfunction in multiple sclerosis. Multiple Sclerosis and Related Disorders, 20: 154–158. 4. Jaftha, M., Robertson, F., van Rensburg, S.J., Kidd, M., van Toorn, R., Kemp, M.C., Johannes, C., Moremi, K.E., Whati, L., Kotze, M.J. & Engel-Hills, P. 2024. White Matter Lesion Volumes on 3‐T MRI in People With MS Who Had Followed a Diet and Lifestyle Program for More Than 10 Years P. Arnett, ed. Multiple Sclerosis International, 2024(1). https://onlinelibrary.wiley.com/doi/10.1155/2024/8818934. 5. Miki, Y. 2019. Magnetic resonance imaging diagnosis of demyelinating diseases: An update. Clinical and Experimental Neuroimmunology, 10(S1): 32–48. 6. Ozturk, A., Smith, S.A., Gordon-Lipkin, E.M., Harrison, D.M., Shiee, N., Pham, D.L., Caffo, B.S., Calabresi, P.A. & Reich, D.S. MRI of the corpus callosum in multiple sclerosis: association with disability. 7. Van Rensburg, S.J., Hattingh, C., Johannes, C., Moremi, K.E., Peeters, A.V., Van Heerden, C.J., Erasmus, R.T., Zemlin, A.E., Kemp, M.C., Jaftha, M., Aye Khine, A., Potocnik, F.C., Whati, L., Engel-Hills, P., Van Toorn, R., Kotze, M.J. & Van Rensburg, S. J. Pathology-supported genetic testing as a method for disability prevention in multiple sclerosis (MS). Part II. Insights from two MS cases. https://doi.org/10.1007/s11011-021-00712-9. 8. Yaldizli, Ö., Penner, I.K., Frontzek, K., Naegelin, Y., Amann, M., Papadopoulou, A., Sprenger, T., Kuhle, J., Calabrese, P., Radü, E.W., Kappos, L. & Gass, A. 2014. The relationship between total and regional corpus callosum atrophy, cognitive impairment, and fatigue in multiple sclerosis patients. Multiple Sclerosis Journal, 20(3): 356–364. [doi]

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http://echo.ismrm.org/p/ISMRM2026/131-01-033