Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
567-06-011 ISMRM Abstract

Altered Magnetic Susceptibility and Oxygen Metabolism in Classical Trigeminal Neuralgia Revealed by QSM and OEF Mapping.

Primary: Neuro - Peripheral Nerves
Secondary: Contrast Mechanisms - Oxygenation
567-06-011 · Novel Contrast Mechanisms II · Wednesday, 13 May, 4:55 PM–5:50 PM · Digital Posters Row H
Keywords: Quantitative Susceptibility mapping Oxygen extraction fraction Classical Trigeminal Neuralgia Microvascular decompression
Accepted
jingqi Jiang1, Xingyu Zhu2, Kai AI3, Jing Zhang 4
1Department of Magnetic Resonance, Lanzhou, China
2School ofInformation Science and Engineering, Lanzhou University, lanzhou, China
3Department of Clinical and Technical Support, Philips Healthcare (Xi'an), Xi'an, China
4Gansu Province Clinical Research Center for Functional and Molecular Imaging, Lanzhou, China, Department of Magnetic Resonance, Lanzhou, China
Presenting Author: Jing Zhang

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References

1. Watanabe M, Shrivastava RK, Balchandani P. Advanced neuroimaging of the trigeminal nerve and the whole brain in trigeminal neuralgia: a systematic review. Pain. 2025;166(2):282-310.
2. Worm J, Heinskou TB, Rochat P, et al. Five-year prospective outcomes of medical management and microvascular decompression in trigeminal neuralgia. J Neurol. 2025;272(10):701.
3. Hod EA, Habeck C, Zhuang H, et al. Effects of iron repletion on brain iron content, myelination, neural network activation, and cognition. JCI Insight. 2025;e194442.
4. McFadden J, Matthews J, Scott L, et al. Compensatory increase in oxygen extraction fraction is associated with age-related cerebrovascular disease. Neuroimage Clin. 2025;45:103746.
5. Cho J, Zhang J, Spincemaille P, et al. QQ-NET - using deep learning to solve quantitative susceptibility mapping and quantitative blood oxygen level dependent magnitude (QSM+qBOLD or QQ) based oxygen extraction fraction (OEF) mapping. Magn Reson Med. 2022;87(3):1583-1594.
6. Mazzitelli M, Ponomareva O, Presto P, et al. Neugebauer V. Impaired amygdala astrocytic signaling worsens neuropathic pain-associated neuronal functions and behaviors. Front Pharmacol. 2024;15:1368634.
7. Ong WY, Stohler CS, Herr DR. Role of the Prefrontal Cortex in Pain Processing. Mol Neurobiol. 2019;56(2):1137-1166.
8. Zhang MM, Geng AQ, Chen K, et al. Glutamatergic synapses from the insular cortex to the basolateral amygdala encode observational pain. Neuron. 2022;110(12):1993-2008.

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/567-06-011