Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
402-03-003 ISMRM Abstract

Pipeline for Quantifying Uncertainty for SPICE Reconstructed MRSI

Accepted
Tian Lyu 1, Saad Jbabdi1, William T Clarke1, Simon M Finney1
1Centre for Integrative Neuroimaging, FMRIB, Nuffield Department of Clinical Neurosciences, University of Oxford, United Kingdom
Presenting Author: Tian Lyu

Synopsis

Motivation:
Goals:
Approach:
Results:
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References

1. Y. Li, Z. Wang, and F. Lam, “SNR Enhancement for Multi-TE MRSI Using Joint Low-Dimensional Model and Spatial Constraints,” IEEE Trans Biomed Eng, vol. 69, no. 10, pp. 3087–3097, Oct. 2022, doi: 10.1109/TBME.2022.3161417. [doi]
2. Y. Li, F. Lam, B. Clifford, and Z. P. Liang, “A subspace approach to spectral quantification for MR spectroscopic imaging,” IEEE Trans Biomed Eng, vol. 64, no. 10, pp. 2486–2489, Oct. 2017, doi: 10.1109/TBME.2017.2741922. [doi]
3. F. Lam, Y. Li, R. Guo, B. Clifford, and Z. P. Liang, “Ultrafast magnetic resonance spectroscopic imaging using SPICE with learned subspaces,” Magn Reson Med, vol. 83, no. 2, pp. 377–390, Feb. 2020, doi: 10.1002/mrm.27980. [doi]
4. F. Lam and Z. P. Liang, “A subspace approach to high-resolution spectroscopic imaging,” Magn Reson Med, vol. 71, no. 4, pp. 1349–1357, 2014, doi: 10.1002/mrm.25168. [doi]
5. Z.-P. Liang, “Spatiotemporal Imaging with Partially Separable Functions,” in 2007 4th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, 2007. doi: 10.1109/ISBI.2007.357020. [doi]
6. J. P. Haldar and Z. P. Liang, “Spatiotemporal imaging with partially separable functions: A matrix recovery approach,” in 2010 7th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2010 - Proceedings, 2010, pp. 716–719. doi: 10.1109/ISBI.2010.5490076. [doi]
7. J. P. Haldar, D. Hernando, S. K. Song, and Z. P. Liang, “Anatomically constrained reconstruction from noisy data,” Magn Reson Med, vol. 59, no. 4, pp. 810–818, 2008, doi: 10.1002/mrm.21536. [doi]
8. W. T. Clarke and M. Chiew, “Uncertainty in denoising of MRSI using low‐rank methods,” Magn Reson Med, vol. 87, no. 2, pp. 574–588, Feb. 2022, doi: 10.1002/mrm.29018. [doi]
9. M. Uecker et al., “Berkeley Advanced Reconstruction Toolbox,” in Proc Intl Soc Mag Reson Med 2015, 2015, p. 23:2486. doi: 10.5281/zenodo.12495. [doi]
10. Y. Wang and S. Li, “Differentiation of metabolic concentrations between gray matter and white matter of human brain by in vivo 1 H magnetic resonance spectroscopy,” Magn Reson Med, vol. 39, no. 1, pp. 28–33, Jan. 1998, doi: 10.1002/mrm.1910390107. [doi]
11. W. T. Clarke, C. J. Stagg, and S. Jbabdi, “FSL-MRS: An end-to-end spectroscopy analysis package,” Magn Reson Med, vol. 85, no. 6, pp. 2950–2964, Jun. 2021, doi: 10.1002/mrm.28630. [doi]
12. Gold Standard Phantoms Ltd., “SPECTRE – Spectroscopy Phantom for Evaluation and Calibration of Technique and Reference,” Gold Standard Phantoms, Sheffield, UK. [Online]. Available: https://goldstandardphantoms.com/products/spectre

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