Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
366-06-003 ISMRM Abstract

Intravoxel Incoherent Motion MRI for Early Detection of Synovitis in Preclinical Rheumatoid Arthritis

Primary: Musculoskeletal - Osteoarthritis
Secondary: Diffusion - IVIM
366-06-003 · Body Diffusion MRI Applications · Monday, 11 May, 5:05 PM–6:00 PM · Digital Posters Row G
Keywords: Preclinical Rheumatoid Arthritis Intravoxel incoherent motion (IVIM)
Accepted
Yunping Yi1, Jun Peng 2, Siwei Zhang1
1Department of Radiology, Traditional Chinese Medicine Hospital of Guangdong Province, Guangzhou, China
2Philips Healthcare, Guangzhou, China
Presenting Author: Jun Peng

Synopsis

Motivation:
Goals:
Approach:
Results:
Full abstract & presentation

The full text, figures, and any recorded presentation for this abstract are not shown here. Log in if you are a member or registered attendee with access.

Full abstracts, figures, and presentations for Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition are available to registered attendees. This content becomes freely available to the public roughly two years after the meeting.

To request or purchase access, contact the ISMRM Central Office at info@ismrm.org.

Log in

References

1. Scott DL, Wolfe F, Huizinga TW (2010) Rheumatoid arthritis. Lancet. DOI:10.1016/S0140-6736(10)60826-4 [doi]
2. Smolen JS, Aletaha D, Barton A et al (2018) Rheumatoid arthritis. Nat Rev Dis Primers. DOI:10.1038/nrdp.2018.1 [doi]
3. Aletaha D, Smolen JS (2018) Diagnosis and Management of Rheumatoid Arthritis: A Review. JAMA. DOI:10.1001/jama.2018.13103 [doi]
4. van der Linden MP, le Cessie S, Raza K et al (2010) Long-term impact of delay in assessment of patients with early arthritis. Arthritis Rheum. DOI:10.1002/art.27692 [doi]
5. Combe B, Landewe R, Daien CI et al (2017) 2016 update of the EULAR recommendations for the management of early arthritis. Ann Rheum Dis. DOI:10.1136/annrheumdis-2016-210602 [doi]
6. Gao KX, Yang YH, Liang Q et al (2024) Targeting Therapeutic Windows for Rheumatoid Arthritis Prevention. Chin J Integr Med. DOI:10.1007/s11655-024-3760-2 [doi]
7. Weyand CM, Goronzy JJ (2021) The immunology of rheumatoid arthritis. Nat Immunol. DOI:10.1038/s41590-020-00816-x [doi]
8. Colebatch AN, Edwards CJ, Ostergaard M et al (2013) EULAR recommendations for the use of imaging of the joints in the clinical management of rheumatoid arthritis. Ann Rheum Dis. DOI:10.1136/annrheumdis-2012-203158 [doi]
9. Wakefield RJ, Balint PV, Szkudlarek M et al (2005) Musculoskeletal ultrasound including definitions for ultrasonographic pathology. J Rheumatol. DOI:
10. McQueen FM, Ostendorf B (2006) What is MRI bone oedema in rheumatoid arthritis and why does it matter? Arthritis Res Ther. DOI:10.1186/ar2075 [doi]
11. Conaghan P, Bird P, Ejbjerg B, et al (2005) The EULAR-OMERACT rheumatoid arthritis MRI reference image atlas: the metacarpophalangeal joints. Ann Rheum Dis. DOI:10.1136/ard.2004.031815 [doi]
12. Le Bihan D, Breton E, Lallemand D, Grenier P, Cabanis E, Laval-Jeantet M (1986) MR imaging of intravoxel incoherent motions: application to diffusion and perfusion in neurologic disorders. Radiology. DOI:10.1148/radiology.161.2.3763909 [doi]
13. Lemke A, Laun FB, Klauss M et al (2009) Differentiation of pancreas carcinoma from healthy pancreatic tissue using multiple b-values: comparison of apparent diffusion coefficient and intravoxel incoherent motion derived parameters. Invest Radiol. DOI:10.1097/RLI.0b013e3181b62271 [doi]
14. Wang Q, Xiao X, Liang Y et al (2021) Diagnostic Performance of Diffusion MRI for differentiating Benign and Malignant Nonfatty Musculoskeletal Soft Tissue Tumors: A Systematic Review and Meta-analysis. J Cancer. DOI:10.7150/jca.62131 [doi]
15. Fujimori M, Murakami K, Sugimori H et al (2019) Intravoxel incoherent motion MRI for discrimination of synovial proliferation in the hand arthritis: A prospective proof-of-concept study. J Magn Reson Imaging. DOI:10.1002/jmri.26660 [doi]
16. Le Bihan D, Breton E, Lallemand D, Aubin ML, Vignaud J, Laval-Jeantet M (1988) Separation of diffusion and perfusion in intravoxel incoherent motion MR imaging. Radiology. DOI:10.1148/radiology.168.2.3393671 [doi]
17. Federau C (2017) Intravoxel incoherent motion MRI as a means to measure in vivo perfusion: A review of the evidence. NMR Biomed. DOI:10.1002/nbm.3780 [doi]
18. Wang LL, Lin J, Liu K et al (2014) Intravoxel incoherent motion diffusion-weighted MR imaging in differentiation of lung cancer from obstructive lung consolidation: comparison and correlation with pharmacokinetic analysis from dynamic contrast-enhanced MR imaging. Eur Radiol. DOI:10.1007/s00330-014-3176-z [doi]
19. rslan S, Ergen FB, Aydin GB et al (2022) Different Attenuation Models of Diffusion-Weighted MR Imaging for the Differentiation of Benign and Malignant Musculoskeletal Tumors. J Magn Reson Imaging. DOI:10.1002/jmri.27887 [doi]
20. Pavilla A, Gambarota G, Signate A, Arrigo A, Saint-Jalmes H, Mejdoubi M (2023) Intravoxel incoherent motion and diffusion kurtosis imaging at 3T MRI: Application to ischemic stroke. Magn Reson Imaging. DOI:10.1016/j.mri.2023.01.018 [doi]
21. Yamashita K, Kamei R, Sugimori H et al (2022) Interobserver Reliability on Intravoxel Incoherent Motion Imaging in Patients with Acute Ischemic Stroke. AJNR Am J Neuroradiol. DOI:10.3174/ajnr.A7486 [doi]
22. Paschoal AM, Leoni RF, Dos SA, Paiva FF (2018) Intravoxel incoherent motion MRI in neurological and cerebrovascular diseases. Neuroimage Clin. DOI:10.1016/j.nicl.2018.08.030 [doi]
23. Wang Q, Yu G, Qiu J, Lu W (2024) Application of Intravoxel Incoherent Motion in Clinical Liver Imaging: A Literature Review. J Magn Reson Imaging. DOI:10.1002/jmri.29086 [doi]
24. Huch B, Stumpf K, Bracher AK et al (2022) Intravoxel incoherent motion (IVIM) MRI in pediatric patients with synovitis of the knee joint: a prospective pilot study. Pediatr Rheumatol Online J. DOI:10.1186/s12969-022-00756-w [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/366-06-003