Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
505-02-004 ISMRM Abstract

Shared and specific structural covariance network disruptions in adolescent and adult major depressive disorder

Primary: Neuro - Psychiatric Disorders
Secondary: Brain Function and fMRI
505-02-004 · Insights into Psychiatric Disorders and the Human Connectome · Wednesday, 13 May, 8:20 AM–10:10 AM · Ballroom West
Keywords: Adolescents 3D T1-weighted imaging Major depressive disorder Individualized Structural Covariance Networks Network Topology
Accepted
Qian Zhang 1, Baolin Wu1, Yuanyuan Li1, Youjin Zhao1, Qiyong Gong2,3
1Department of Radiology, Huaxi MR Research Center (HMRRC), Institute of Radiology, Functional and Molecular Imaging Key Laboratory of Sichuan Province, West China Hospital of Sichuan University, Chengdu, China
2Huaxi MR Research Center (HMRRC), Functional and Molecular Imaging Key Laboratory of Sichuan Province, West China Hospital of Sichuan University, Chengdu, China
3Xiamen Key Laboratory of Psychoradiology and Neuromodulation, Department of Radiology, West China Xiamen Hospital of Sichuan University, Xiamen, China
Presenting Author: Qian Zhang

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References

1. Rice F, Riglin L, Lomax T, et al. Adolescent and adult differences in major depression symptom profiles. J Affect Disord. 2019;243:175-181.
2. Alexander-Bloch A, Giedd JN, Bullmore E. Imaging structural co-variance between human brain regions. Nat Rev Neurosci. 2013;14(5):322-336.
3. Sebenius I, Dorfschmidt L, Seidlitz J, Alexander-Bloch A, Morgan SE, Bullmore E. Structural MRI of brain similarity networks. Nat Rev Neurosci. 2025;26(1):42-59.
4. Wang H, Jin X, Zhang Y, Wang J. Single-subject morphological brain networks: connectivity mapping, topological characterization and test-retest reliability. Brain Behav. 2016;6(4):e00448.
5. Liu Z, Rolls ET, Liu Z, et al. Brain annotation toolbox: exploring the functional and genetic associations of neuroimaging results. Bioinformatics. 2019;35(19):3771-3778.
6. Paus T, Keshavan M, Giedd JN. Why do many psychiatric disorders emerge during adolescence? Nat Rev Neurosci. 2008;9(12):947-957.

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/505-02-004