Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
460-01-005 ISMRM Abstract

Using calibrated BOLD to measure transient changes in the metabolic rate of oxygen: comparing CBF-venous CBV coupling models

Primary: Brain Function and fMRI - fMRI Analysis
Secondary: Brain Function and fMRI - Task/Intervention Based fMRI
460-01-005 · Brain Physiology and Pain · Tuesday, 12 May, 8:20 AM–9:15 AM · Digital Posters Row A
Keywords: Brain Connectivity fMRI (resting state) fMRI (task based) Metabolism Modelling
Accepted
Yasaman Shafaee 1,2, J. Jean Chen3,4,5, Avery Berman1,2
1Physics, Carleton University, Ottawa, Canada
2University of Ottawa Institute of Mental Research at The Royal, Ottawa, Canada
3Rotman Research Institute at Baycrest, Toronto, Canada
4Biomedical Engineering, University of Toronto, Toronto, Canada
5Department of Medical Biophysics, University of Toronto, Toronto, Canada
Presenting Author: Yasaman Shafaee

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References

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6. Huppert, T.J., Allen, M.S., Benav, H., Jones, P.B. and Boas, D.A., 2007. A multicompartment vascular model for inferring baseline and functional changes in cerebral oxygen metabolism and arterial dilation. Journal of cerebral blood flow & metabolism, 27(6), pp.1262-1279. doi: 10.1038/sj.jcbfm.9600435. [doi]
7. Sten, S., Podéus, H., Sundqvist, N., Elinder, F., Engström, M. and Cedersund, G., 2023. A quantitative model for human neurovascular coupling with translated mechanisms from animals. PLOS Computational Biology, 19(1), p.e1010818. doi: 10.1371/journal.pcbi.1010818 [doi]
8. Chen, J.J. and Pike, G.B., 2009. Origins of the BOLD post-stimulus undershoot. Neuroimage, 46(3), pp.559-568. doi: 10.1016/j.neuroimage.2012.06.054 [doi]
9. Stefanovic, B. and Pike, G.B., 2005. Venous refocusing for volume estimation: VERVE functional magnetic resonance imaging. Magnetic Resonance in Medicine: An Official Journal of the International Society for Magnetic Resonance in Medicine, 53(2), pp.339-347. doi: 10.1038/jcbfm.2012.63 [doi]
10. Shafaee, Y., Hartung, G., Berman , A. 2024 The dynamic relationship between cerebral blood flow and venous cerebral blood volume under different types of stimuli. ISMRM Abstract #5187
11. Chu, P. P., Golestani, A. M., Kwinta, J. B., Khatamian, Y. B., & Chen, J. J. (2018). Characterizing the modulation of resting-state fMRI metrics by baseline physiology. Neuroimage, 173, 72-87. doi: 10.1016/j.neuroimage.2018.02.004. [doi]

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http://echo.ismrm.org/p/ISMRM2026/460-01-005