Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
468-02-006 ISMRM Abstract

MRI Volumetric Assessment of Brain Subcortical Deep Grey Nuclei in Type I and Type 2 Diabetes Using Normative Modeling

Primary: Neuro - Gray Matter
Secondary: Analysis Methods - Segmentation and Detection
468-02-006 · Type 2 Diabetes · Tuesday, 12 May, 9:15 AM–10:10 AM · Digital Posters Row I
Keywords: Type 2 diabetes mellitus Normative modeling Type 1 diabetes mellitus Deep gray matter nuclei Volumetric Analysis
Accepted
Mohammed Salman Shazeeb 1, manojkumar saranathan1,2, Hanan Al-Awadhi3,4, Ahmad Awwad3, Arit Banerjee1, Batool Alesmaeel3, Husain Alsaraf3, Anant Mashankar3, Dalal Alsaeed3, Ebaa Alozairi3, Abdulla Alozairi3,4
1Department of Radiology, University of Massachusetts Chan Medical School, Worcester, United States of America
2Department of Neurology, UMass Chan Medical School, Worcester, United States of America
3Dasman Diabetes Institute, Kuwait City, Kuwait
4Kuwait University, Kuwait City, Kuwait
Presenting Author: Mohammed Salman Shazeeb

Synopsis

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References

1. Hossain MJ, Al-Mamun M, Islam MR. Diabetes mellitus, the fastest growing global public health concern: Early detection should be focused. Health Sci Rep. 2024 Mar 22;7(3):e2004. doi: 10.1002/hsr2.2004. PMID: 38524769; PMCID: PMC10958528. [doi] [pmid]
2. Mahmood S, Dkhar W, Kadavigere R, Sukumar S, Nayak K, Pradhan A, Ravichandran S, Barnes NA, Shettigar D. An analysis of brain structural changes in type 2 diabetes using advanced MRI techniques. Magn Reson Imaging. 2025 Sep;121:110419. doi: 10.1016/j.mri.2025.110419. Epub 2025 May 8. PMID: 40348298. [doi] [pmid]
3. Dai P, Yu Y, Sun Q, Yang Y, Hu B, Xie H, Li SN, Cao XY, Ni MH, Cui YY, Bai XY, Bi JJ, Cui GB, Yan LF. Abnormal changes of brain function and structure in patients with T2DM-related cognitive impairment: a neuroimaging meta-analysis and an independent validation. Nutr Diabetes. 2024 Nov 11;14(1):91. doi: 10.1038/s41387-024-00348-5. PMID: 39528442; PMCID: PMC11554684. [doi] [pmid]
4. Saranathan M, Cogliandro G, Hicks T, Patterson D, Vachha B, Hader A, Shazeeb MS, Cacciola A. Comprehensive Segmentation of Deep Grey Nuclei From Structural MRI Data. Hum Brain Mapp. 2025 Oct 1;46(14):e70350. doi: 10.1002/hbm.70350. PMID: 40985796; PMCID: PMC12455863. [doi] [pmid]
5. Young T, Kumar VJ, Saranathan M. Normative modeling of thalamic nuclear volumes. medRxiv [Preprint]. 2024 Mar 8:2024.03.06.24303871. doi: 10.1101/2024.03.06.24303871. Update in: Biol Psychiatry Cogn Neurosci Neuroimaging. 2025 Jul;10(7):726-739. doi: 10.1016/j.bpsc.2024.08.006. PMID: 38496426; PMCID: PMC10942522. [doi] [pmid]

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http://echo.ismrm.org/p/ISMRM2026/468-02-006