Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
465-02-009 Registered Abstract

Evaluating wall shear stress in rheumatic heart disease using 4D Flow MRI and computational fluid dynamics

Primary: Cardiovascular - Flow
Secondary: Cardiovascular - Valves
465-02-009 · Novel Developments and Applications in Flow MRI · Tuesday, 12 May, 9:15 AM–10:10 AM · Digital Posters Row F
Keywords: Valves 4D flow MRI Cardiovascular magnetic resonance Aortic stenosis Mitral regurgitation
Accepted
Thandiwe T Zhanje 1,2,3, Stephen Jermy1,2,3, Jordan Bougardt4, Ernesta Meintjes1,2,3, Ntobeko Ntusi2,5,6,7
1Biomedical Engineering Research Centre, Division of Biomedical Engineering, Department of Human Biology, University of Cape Town, Cape Town, South Africa
2Cape Universities Body Imaging Centre (CUBIC), University of Cape Town, Cape Town, South Africa
3Neuroscience Institute, University of Cape Town, South Africa, South Africa
4Department of Mechanical Engineering, Centre for research in computational and applied mechanics (CERECAM), University of Cape Town, Cape Town, South Africa
5Cape Heart Institute, Department of Medicine, University of Cape Town, Cape Town, South Africa
6Division of Cardiology, University of Cape Town and Groote Schuur Hospital, Cape Town, South Africa
7South African Medical Research Council, Cape Town, South Africa
Presenting Author: Thandiwe T Zhanje

Synopsis

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References

1. Roberts, K., Colquhoun, S., Steer, A., Reményi, B., & Carapetis, J. (2013). Screening for rheumatic heart disease: current approaches and controversies. Nature Reviews Cardiology, 10(1), 49-58. doi: 10.1038/nrcardio.2012.157 [doi]
2. Peters, F., Karthikeyan, G., Abrams, J., Muhwava, L., & Zühlke, L. (2020). Rheumatic heart disease: current status of diagnosis and therapy. Cardiovascular diagnosis and therapy, 10(2), 305. doi: 10.21037/cdt.2019.10.07 [doi]
3. Cebull, H. L., Aremu, O. O., Kulkarni, R. S., Zhang, S. X., Samuels, P., Jermy, S., ... & Goergen, C. J. (2023). Simulating subject-specific aortic hemodynamic effects of valvular lesions in rheumatic heart disease. Journal of Biomechanical Engineering, 145(11), 111003.
4. Schnell, S., Ansari, S. A., Wu, C., Garcia, J., Murphy, I. G., Rahman, O. A., ... & Markl, M. (2017). Accelerated dual‐venc 4D flow MRI for neurovascular applications. Journal of Magnetic Resonance Imaging, 46(1), 102-114. doi: 10.1002/jmri.25595 [doi]
5. Bissell, M. M., Raimondi, F., Ait Ali, L., Allen, B. D., Barker, A. J., Bolger, A., ... & Dyverfeldt, P. (2023). 4D Flow cardiovascular magnetic resonance consensus statement: 2023 update. Journal of Cardiovascular Magnetic Resonance, 25(1), 40. doi: 10.1186/s12968-023-00942-z [doi]
6. Dyverfeldt, P., & Ebbers, T. (2017). Comparison of respiratory motion suppression techniques for 4D flow MRI. Magn Reson Med, 78(5), 1877-1882. https://doi.org/10.1002/mrm.26574 [doi]
7. Isoda, H., & Fukuyama, A. (2022). Quality Control for 4D Flow MR Imaging. Magn Reson Med Sci, 21(2), 278-292. https://doi.org/10.2463/mrms.rev.2021-0165 [doi]
8. Zimmermann, J., Demedts, D., Mirzaee, H., Ewert, P., Stern, H., Meierhofer, C., Menze, B., & Hennemuth, A. (2018). Wall shear stress estimation in the aorta: Impact of wall motion, spatiotemporal resolution, and phase noise. Journal of Magnetic Resonance Imaging, 48(3), 718-728

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http://echo.ismrm.org/p/ISMRM2026/465-02-009