Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026
· Cape Town, South Africa
562-01-007
ISMRM Abstract
Non-Contrast-Enhanced 4D Ventilation Mapping from Highly Accelerated Time-Resolved 4D MRI of the lungs
Primary:
Body - Lung
Secondary:
Acquisition & Reconstruction - Image Reconstruction: AI
562-01-007 · Lung and Thoracic Oncological MRI
· Wednesday, 13 May, 8:20 AM–9:15 AM · Digital Posters Row C
Keywords:Scan time reductionRapid imagingLung MRIAI-Accelerated MRI4D ventilation
Accepted
Filip Klimeš 1,2,3, Andreas Voskrebenzev1,2, Jingjia Chen4, Frank Wacker1,2, Hersh Chandarana4, Jens Vogel-Claussen1,2,3, Li Feng4
1Institute of Diagnostic and Interventional Radiology, Hannover Medical School, Hannover, Germany
2Member of the German Centre for Lung Research, Biomedical Research in Endstage and Obstructive Lung Disease, Hannover, Germany
3Department of Radiology, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany
4Center for Advanced Imaging Innovation and Research (CAI2R), Department of Radiology, New York University Grossman School of Medicine, New York, United States of America
Presenting Author: Filip Klimeš
Synopsis
Motivation:
Goals:
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1. Voskrebenzev A, Gutberlet M, Klimeš F, et al. Feasibility of quantitative regional ventilation and perfusion mapping with phase-resolved functional lung (PREFUL) MRI in healthy volunteers and COPD, CTEPH, and CF patients. Magn Reson Med. 2018;79(4):2306-2314. doi:10.1002/mrm.26893 [doi]
2. Klimeš F, Voskrebenzev A, Gutberlet M, et al. 3D phase‐resolved functional lung ventilation MR imaging in healthy volunteers and patients with chronic pulmonary disease. Magn Reson Med. 2021;85(2):912-925. doi:10.1002/mrm.28482 [doi]
3. Feng L. 4D Golden-Angle Radial MRI at Subsecond Temporal Resolution. NMR Biomed. 2023;36(2):1-18. doi:10.1002/nbm.4844 [doi]
4. Feng L. Live-view 4D GRASP MRI: A framework for robust real-time respiratory motion tracking with a sub-second imaging latency. Magn Reson Med. 2023;90(3):1053-1068. doi:10.1002/mrm.29700 [doi]
5. Feng L, Wen Q, Huang C, Tong A, Liu F, Chandarana H. GRASP-Pro: imProving GRASP DCE-MRI through self-calibrating subspace-modeling and contrast phase automation. Magn Reson Med. 2020;83(1):94-108. doi:10.1002/mrm.27903 [doi]
6. Voskrebenzev A, Gutberlet M, Kaireit TF, Wacker F, Vogel-Claussen J. Low-pass imaging of dynamic acquisitions (LIDA) with a group-oriented registration (GOREG) for proton MR imaging of lung ventilation. Magn Reson Med. 2017;78(4):1496-1505. doi:10.1002/mrm.26526 [doi]
7. Forsberg D. fordanic/image-registration (https://github.com/fordanic/image-registration), GitHub. Retrieved September 8, 2021.
8. Klimeš F, Voskrebenzev A, Gutberlet M, et al. Free‐breathing quantification of regional ventilation derived by phase‐resolved functional lung (PREFUL) MRI. NMR Biomed. 2019;(February):e4088. doi:10.1002/nbm.4088 [doi]
9. Klimeš F, Voskrebenzev A, Gutberlet M, et al. Repeatability of dynamic 3D phase-resolved functional lung (PREFUL) ventilation MR Imaging in patients with chronic obstructive pulmonary disease and healthy volunteers. J Magn Reson Imaging. 2021;54(2):618-629. doi:10.1002/jmri.27543 [doi]
10. Klimeš F, Foo CT, Gutberlet M, et al. Dual-Center Repeatability, Consistency, and Comparison of 3D Phase-Resolved Functional (PREFUL) Ventilation MRI at 3 and 1.5 T in Healthy Volunteers. NMR Biomed. 2025;38(9). doi:10.1002/nbm.70101 [doi]