Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
363-06-001 ISMRM Abstract

Hemodynamics and Endomyocardial Injury in Severe Aortic Stenosis: Insights from 4D Flow CMR, catheter Pressure and histologic

Primary: Cardiovascular - Flow
Secondary: Cardiovascular - Valves
363-06-001 · Hemodynamics and Flow · Monday, 11 May, 5:05 PM–6:00 PM · Digital Posters Row D
Keywords: 4D flow MRI Aortic stenosis Hemodynamics Myocardial fibrosis
Accepted
Ying Zhong 1, Daniel Giese2,3, Yunzhu Wu4, Yueluan Jiang5, Guan Wang1
1Radiology, The First Hospital of China Medical University, Shenyang, China
2Siemens Healthineers AG, Erlangen, Germany
3MR Research & Clinical Translation, Siemens Healthineers AG, Erlangen, Germany
4MR Research Collaboration Team, Shanghai, China
5MR Research Collaboration Team, Siemens Healthineers Ltd., Beijing, China
Presenting Author: Ying Zhong

Synopsis

Motivation:
Goals:
Approach:
Results:
Full abstract & presentation

The full text, figures, and any recorded presentation for this abstract are not shown here. Log in if you are a member or registered attendee with access.

Full abstracts, figures, and presentations for Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition are available to registered attendees. This content becomes freely available to the public roughly two years after the meeting.

To request or purchase access, contact the ISMRM Central Office at info@ismrm.org.

Log in

References

1. Yang S, Zhao K, Yang K, Song J, Yu S, Wang J, Dong Z, Ma X, Yin G, Li J, Cheng H, Lu M, Chen X, Zhao S. Subendocardial Involvement as an Underrecognized LGE Subtype Related to Adverse Outcomes in Hypertrophic Cardiomyopathy. JACC Cardiovasc Imaging. 2023 Sep;16(9):1163-1177. doi: 10.1016/j.jcmg.2023.03.011. [doi]
2. Zhong Y, Long Q, Zeng M, Wu L, Guo L, Wang G. Feature-Tracking-Derived Strain Analysis for Identification of Subendocardium-Involved Late Gadolinium Enhancement in Load-Induced Left Ventricular Hypertrophy: A Multicenter Study of Cardiac Magnetic Resonance Data. J Clin Med. 2023 Dec 7;12(24):7543. doi: 10.3390/jcm12247543. [doi]
3. Maron MS, Olivotto I, Maron BJ, Prasad SK, Cecchi F, Udelson JE, Camici PG. The case for myocardial ischemia in hypertrophic cardiomyopathy. J Am Coll Cardiol. 2009 Aug 25;54(9):866-75. doi: 10.1016/j.jacc.2009.04.072. [doi]
4. Rajesh GN, Thottian JJ, Subramaniam G, Desabandhu V, Sajeev CG, Krishnan MN. Prevalence and prognostic significance of left ventricular myocardial late gadolinium enhancement in severe aortic stenosis. Indian Heart J. 2017 Nov-Dec;69(6):742-750. doi: 10.1016/j.ihj.2017.05.027. [doi]
5. Abecasis J, Maltês S, Santos RR, Lopes P, Manso RT, Gil V, Cardim N, Ramos S, Félix A. Subendocardial "ischemic-like" state in patients with severe aortic stenosis: Insights from myocardial histopathology and ultrastructure. Cardiovasc Pathol. 2024 Mar-Apr;69:107589. doi: 10.1016/j.carpath.2023.107589. [doi]
6. Zhou M, Yu Y, Chen R, Liu X, Hu Y, Ma Z, Gao L, Jian W, Wang L. Wall shear stress and its role in atherosclerosis. Front Cardiovasc Med. 2023 Apr 3;10:1083547. doi: 10.3389/fcvm.2023.1083547. [doi]
7. Adamopoulos D, Rovas G, Johner N, Müller H, Deux JF, Crowe LA, Vallée JP, Mach F, Stergiopulos N, Shah D. Left atrial wall shear stress correlates with fibrosis in patients with atrial fibrillation. Nat Cardiovasc Res. 2025 Jun;4(6):677-688. doi: 10.1038/s44161-025-00651-z. [doi]
8. Treibel TA, López B, González A, Menacho K, Schofield RS, Ravassa S, Fontana M, White SK, DiSalvo C, Roberts N, Ashworth MT, Díez J, Moon JC. Reappraising myocardial fibrosis in severe aortic stenosis: an invasive and non-invasive study in 133 patients. Eur Heart J. 2018 Feb 21;39(8):699-709. doi: 10.1093/eurheartj/ehx353. [doi]
9. Bissell MM, Raimondi F, Ait Ali L, Allen BD, Barker AJ, Bolger A, Burris N, Carhäll CJ, Collins JD, Ebbers T, Francois CJ, Frydrychowicz A, Garg P, Geiger J, Ha H, Hennemuth A, Hope MD, Hsiao A, Johnson K, Kozerke S, Ma LE, Markl M, Martins D, Messina M, Oechtering TH, van Ooij P, Rigsby C, Rodriguez-Palomares J, Roest AAW, Roldán-Alzate A, Schnell S, Sotelo J, Stuber M, Syed AB, Töger J, van der Geest R, Westenberg J, Zhong L, Zhong Y, Wieben O, Dyverfeldt P. 4D Flow cardiovascular magnetic resonance consensus statement: 2023 update. J Cardiovasc Magn Reson. 2023 Jul 20;25(1):40. doi: 10.1186/s12968-023-00942-z. [doi]
10. Bańka P, Wybraniec M, Bochenek T, Gruchlik B, Burchacka A, Swinarew A, Mizia-Stec K. Influence of Aortic Valve Stenosis and Wall Shear Stress on Platelets Function. J Clin Med. 2023 Sep 29;12(19):6301. doi: 10.3390/jcm12196301. [doi]
11. Dong L, Li H, Xu X, Ren M, Yu W, Bai W, Sun D, Tian J. Analysis of diastolic left ventricular wall shear stress in normal people of different age groups. Front Cardiovasc Med. 2022 Sep 23;9:953384. doi: 10.3389/fcvm. [doi]
12. Stoll VM, Hess AT, Rodgers CT, Bissell MM, Dyverfeldt P, Ebbers T, Myerson SG, Carlhäll CJ, Neubauer S. Left Ventricular Flow Analysis. Circ Cardiovasc Imaging. 2019 May;12(5):e008130. doi: 10.1161/CIRCIMAGING.118.008130. [doi]
13. Wang L, Liu M, Zhang PY, Dai JZ, Ma HY, Tao XC, Xie WM, Wan J, Jing A. Analysis of right ventricular flow with 4-dimensional flow cardiovascular magnetic resonance imaging in patients with pulmonary arterial hypertension. Quant Imaging Med Surg. 2021 Aug;11(8):3655-3665. doi: 10.21037/qims-20-1267. [doi]
14. Everett RJ, Treibel TA, Fukui M, Lee H, Rigolli M, Singh A, Bijsterveld P, Tastet L, Musa TA, Dobson L, Chin C, Captur G, Om SY, Wiesemann S, Ferreira VM, Piechnik SK, Schulz-Menger J, Schelbert EB, Clavel MA, Newby DE, Myerson SG, Pibarot P, Lee S, Cavalcante JL, Lee SP, McCann GP, Greenwood JP, Moon JC, Dweck MR. Extracellular Myocardial Volume in Patients With Aortic Stenosis. J Am Coll Cardiol. 2020 Jan 28;75(3):304-316. doi: 10.1016/j.jacc.2019.11.032. [doi]
15. Abecasis J, Lopes P, Maltes S, Santos RR, Ferreira A, Ribeiras R, Andrade MJ, Uva MS, Gil V, Félix A, Ramos S, Cardim N. Histopathological myocardial changes in patients with severe aortic stenosis referred for surgical valve replacement: a cardiac magnetic resonance correlation study. Eur Heart J Cardiovasc Imaging. 2024 May 31;25(6):839-848. doi: 10.1093/ehjci/jeae023. [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/363-06-001