460-01-012 ISMRM Abstract

Mechanical Pressure Pain Evokes Predominantly Phasic Onset Responses Across Brain and Spinal Cord

Primary: Brain Function and fMRI - fMRI Analysis

Secondary: Analysis Methods - Data Processing

460-01-012 · Brain Physiology and Pain · Tuesday, 12 May, 8:20 AM–9:15 AM · Digital Posters Row A

Keywords: Spinal Cord fMRI Spinal cord-brain connectivity Finite impulse response analysis Noxious pain fMRI Fmri temporal dynamics

Accepted

Christine S W Law ¹, Dario Pfyffer¹, Merve Kaptan¹, Xue Zhang², Kenneth Weber¹, Sean Mackey¹, Gary H Glover³

¹Department of Anesthesiology, Perioperative and Pain Medicine, Stanford University, Stanford, United States of America

²Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, United States of America

³Department of Radiology, Stanford University, Stanford, United States of America

Presenting Author: Christine S W Law

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References

1. 1. (ISMRM 2022) Pressure Pain Activation Revealed in Simultaneous Brain, High-Res Brainstem, and High-Res Spinal Cord fMRI. https://archive.ismrm.org/2022/1868.html.

2. 2. Nold, J.I., Tinnermann, A., Fadai, T., Mintah, M., Morgenroth, M.-S., and Büchel, C. (2025). Comparing neural responses to cutaneous heat and pressure pain in healthy participants. Sci. Rep. 15, 14387. https://doi.org/10.1038/s41598-025-99247-7. [doi]

3. 3. Islam, H., Law, C.S.W., Weber, K.A., Mackey, S.C., and Glover, G.H. (2018). Dynamic per slice Shimming for Simultaneous Brain and Spinal Cord fMRI. Magn. Reson. Med. https://doi.org/10.1002/mrm.27388. [doi]

4. 4. Glover, G.H., Li, T.Q., and Ress, D. (2000). Image-based method for retrospective correction of physiological motion effects in fMRI: RETROICOR. Magn. Reson. Med. 44, 162–167.

5. 5. Jenkinson, M., Beckmann, C.F., Behrens, T.E., Woolrich, M.W., and Smith, S.M. (2012). FSL. Neuroimage 62, 782–790. https://doi.org/10.1016/j.neuroimage.2011.09.015. [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/460-01-012