Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
131-01-031 ISMRT Abstract

Ultra-high contrast MRI (UHC-MRI) on different vendors' systems – The link between physics and the whiteout sign

131-01-031 · Lunch, Exhibition & Poster Tour · Saturday, 9 May, 12:30 PM–2:00 PM · Roof Terrace
Keywords: Acquisition Methods Contrast Mechanisms MTBI Magnetization transfer (MT) White matter contrast
Accepted
Paul M Condron 1,2, Daniel Cornfeld1,2, Eryn Kwon1,3, Tracy Melzer2,4,5, Miriam Scadeng2, Mark Bydder1, Samantha Holdsworth1,2,3, Graeme M Bydder1,6
1Mātai Medical Research Institute, Gisborne, New Zealand
2University of Auckland, Auckland, New Zealand
3Auckland Bioengineering Institute, University of Auckland, Auckland, New Zealand
4University of Otago, Christchurch, New Zealand
5University of Canterbury, Christchurch, New Zealand
6University of California, San Diego, United States of America
Presenting Author: Paul M Condron

Synopsis

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References

1. 1. Newburn G, McGeown JP, Kwon EE et al. Targeted MRI (tMRI) of small increases in the T1 of normal appearing white matter in mild traumatic brain injury (mTBI) using a divided subtracted inversion recovery (dSIR) sequence. OBM Neurobiology 2023; 7(4): doi: 10.21926/obm.neurobiol.2304201. [doi]
2. 2. Cornfeld DM, Newburn G, Condron P et al. Ultra-high contrast MRI: a new technique for recognizing secondary changes to the brain in patients with persistent symptoms following traumatic injury. Neuroradiology (in press).
3. 3. Newburn G, Condron P, Kwon EE et al. Diagnosis of delayed post-hypoxic leukoencephalopathy (Grinker's myelinopathy) with MRI using divided subtracted inversion recovery (dSIR) sequences: time for reappraisal of the syndrome? Diagnostics 2024;14(4):418. https://doi.org/10.3390/diagnostics14040418. [doi]
4. 4. Cornfeld DM, Condron P, Bydder M et al. Ultra-high contrast MRI of the brain and spinal cord using directly acquired and synthetic bipolar inversion recovery (BLAIR) images. Preprints 2025. doi:10.20944/preprints202505.2380.v6. [doi]
5. 5. Condron P, Cornfeld DM, Bydder M et al. Ultra-High Contrast (UHC) MRI of the brain, spinal cord and optic nerves in multiple sclerosis using directly acquired and synthetic bipolar filter (BLAIR) images. Diagnostics 2025, 15, 329. https://doi.org/10.3390/diagnostics15030329 [doi]
6. 6. Bydder M, Girard OM, Melzer TR, et al. The Role of Incidental Magnetization Transfer in Divided Subtracted Inversion Recovery. NMR Biomed. 2025;38(12):e70165. doi:10.1002/nbm.70165 [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/131-01-031