Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
470-11-157 ISMRM Abstract

Bile acids detection by 1H-MRS in patients with various cholesterol levels

Primary: Body - Biliary
Secondary: Contrast Mechanisms - Spectroscopy
470-11-157 · Spectroscopy Traditional Posters · Tuesday, 12 May, 4:55 PM–5:50 PM · Traditional Posters | Exhibition Hall
Keywords: Single voxel spectroscopy In vivo proton magnetic resonance spectroscopy Gallbladder Hypercholesterolemia Bile acids
Accepted
Ivica Just 1, Luise Bellach1, Sarah Hofer-Zeni1, Radka Klepochová1,2,3,4,5, Alexandra Kautzky-Willer1, Martin Krssak1,5, Michael Leutner1
1Clinical Division of Internal Medicine III, Vienna, Austria
2Institute of Measurement Science, Slovak academy Academy, Bratislava, Slovakia
3Institute of Measurement Science, Slovak Academy of Sciences, Bratislava, Slovakia
4Institute of Experimental Endocrinology, Biomedical Research Center, Slovak Academy of Sciences, Bratislava, Slovakia
5Medical University of Vienna, Vienna, Austria
Presenting Author: Ivica Just

Synopsis

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References

1. Ijare OB, Bezabeh T, Albiin N et al. Simultaneous quantification of glycine- and taurine-conjugated bile acids, total bile acids, and choline-containing phospholipids in human bile using 1H NMR spectroscopy, Journal of Pharmaceutical and Biomedical Analysis. 2010. 53 (3):667-673, https://doi.org/10.1016/
2. Mohajeri S, Bezabeh T, Ijra OM et al. In Vivo 1H MRS of human gallbladder bile in understanding the pathophysiology of primary sclerosing cholangitis (PSC): immunie-mediated disease versus bile acid-induced injury. NMR in Biomedicine. 2018; 21:e4065, DOI: 10.1002/nbm.4065 [doi]
3. Vermathen,P, Diserens G, Kröll D et al. Determination of bile acids from human gallbladder by 1H-MRS-Protocol optimization and estimation of reproducibility. NMR in Biomedicine, 2019; 34:e4432, DOI: 10.1002/nbm.4432 [doi]
4. Gajdosik M, Chmelik M, Halibasic E et al. In Vivo 1H MRSpectroscopy of Billiary Components of Human Gallbaldder at 7T. J Magn Reson Imaging. 2020; 53:98-107, DOI: 10.1002/jmri.27207 [doi]
5. Just I, Leutner M, Wampl S et al. In vivo measurement of bile metabolite concentrations at 3T by 1H single voxel STEAM MRS- breating triggered navigation vs breath-hold acquisition. In: Proc. Intl. Soc. Mag. Reson. Med. 30 (2022) ISMRM-ESMRMB, 2022, DOI: https://doi.org/10.58530/2022/0031 [doi]
6. Chiang JYL. Bile acids: regulation of synthesis: Thematic Review Series: Bile Acids,Journal of Lipid Research, 2009; 50 (10): 1955-1966, DOI: 10.1194/jlr.R900010-JLR200 [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/470-11-157