Bhavana S Solanky 1,2, Michael Brightman1, Sara Collorone1, Ferran Prados Carrasco1,3, Samuel Rot1,2, Antonio Ricciardi1, Ahmed Toosy1, Claudia A Gandini Wheeler-Kingshott
1NMR Research unit, Queen Square Multiple Sclerosis Centre, Department of Neuroinflammation, UCL Queen Square Institute of Neurology, Faculty of Brain Sciences, University College London, London, United Kingdom
2Hawkes Institute, Department of Medical Physics and Biomedical Engineering, University College London, London, United Kingdom
3Department of Medical Physics and Biomedical Engineering, University College London, London, United Kingdom
Presenting Author: Bhavana S Solanky
Synopsis
Motivation:
Goals:
Approach:
Results:
Full abstract & presentation
The full text, figures, and any recorded presentation for this abstract are not shown here. Log in if you are a member or registered attendee with access.
Full abstracts, figures, and presentations for Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition are available to registered attendees. This content becomes freely available to the public roughly two years after the meeting.
To request or purchase access, contact the ISMRM Central Office at info@ismrm.org.
1. Zaaraoui W, Konstandin S, Audoin B, Nagel AM, Rico A, Malikova I, Soulier E, Viout P, Confort-Gouny S, Cozzone PJ, Pelletier J, Schad LR, Ranjeva JP. Distribution of brain sodium accumulation correlates with disability in multiple sclerosis: a cross-sectional 23Na MR imaging study. Radiology. 2012 Sep;264(3):859-67. doi: 10.1148/radiol.12112680. Epub 2012 Jul 17. PMID: 22807483. [doi][pmid]
2. Inglese M, Madelin G, Oesingmann N, Babb JS, Wu W, Stoeckel B, Herbert J, Johnson G. Brain tissue sodium concentration in multiple sclerosis: a sodium imaging study at 3 tesla. Brain. 2010 Mar;133(Pt 3):847-57. doi: 10.1093/brain/awp334. Epub 2010 Jan 27. PMID: 20110245; PMCID: PMC2842511. [doi][pmid]
3. Paling D, Solanky BS, Riemer F, Tozer DJ, Wheeler-Kingshott CA, Kapoor R, Golay X, Miller DH. Sodium accumulation is associated with disability and a progressive course in multiple sclerosis. Brain. 2013 Jul;136(Pt 7):2305-17. doi: 10.1093/brain/awt149. PMID: 23801742. [doi][pmid]
4. Solanky, B. S, Alves Da Mota, P, Prados, F, Schneider, T, Riemer, F, Brownlee, W, Grussu, F., Cardoso, M. J, Ourselin, S, Zhang, H, Miller, D. H, Golay, X, Gandini Wheeler-Kingshott, C. A. M. Combined Sodium NODDI: Towards quantitative in vivo intracellular and intraneurite sodium measures at 3T, ISMRM 23rd Annual Meeting & Exhibition Toronto, CANADA 2015
5. 5) Dufour J, Hamzaoui M, Lazzaroto A, Theodore Soulier T, Porciuncula Baptista R, Vignaud A, Boffa G, Inglese M, Romanzetti S, Asllani I, Cercignani M, Boumezbeur F, Stankoff B, Bodini B, Before it’s too late: dynamic changes in sodium (23Na) neurite-fractions uncover the phase of potentially reversible cellular energy distress preceding neurodegeneration in multiple sclerosis, Book of Abstracts ESMRMB 2024 Online 40th Annual Scientific Meeting 2–5 October 2024. Magn Reson Mater Phy 37 (Suppl 1), 143 (2024). https://doi.org/10.1007/s10334-024-01191-6 [doi]
6. Zhang H, Schneider T, Wheeler-Kingshott CA, Alexander DC. NODDI: practical in vivo neurite orientation dispersion and density imaging of the human brain. Neuroimage. 2012 Jul 16;61(4):1000-16. doi: 10.1016/j.neuroimage.2012.03.072. Epub 2012 Mar 30. PMID: 22484410. [doi][pmid]
7. Riemer F, Solanky BS, Stehning C, Clemence M, Wheeler-Kingshott CA, Golay X. Sodium ((23)Na) ultra-short echo time imaging in the human brain using a 3D-Cones trajectory. MAGMA. 2014 Feb;27(1):35-46. doi: 10.1007/s10334-013-0395-2. Epub 2013 Jul 31. PMID: 23900703; PMCID: PMC3912357. [doi][pmid]
8. Brownlee WJ, Solanky B, Prados F, Yiannakas M, Da Mota P, Riemer F, Cardoso MJ, Ourselin S, Golay X, Gandini Wheeler-Kingshott C, Ciccarelli O. Cortical grey matter sodium accumulation is associated with disability and secondary progressive disease course in relapse-onset multiple sclerosis. J Neurol Neurosurg Psychiatry. 2019 Jul;90(7):755-760. doi: 10.1136/jnnp-2018-319634. Epub 2019 Apr 4. PMID: 30948625; PMCID: PMC7611428. [doi][pmid]
9. Cardoso, M. J., Wolz, R., Modat, M., Fox, N. C., Rueckert, D. & Ourselin, S., Geodesic Information Flows1 Jan 2012, Medical Image Computing and Computer-Assisted Intervention - MICCAI2012 - 15th International Conference, Proceedings. Springer Verlag, Vol. 7511 LNCS. p. 262-270
10. Modat M, Cash DM, Daga P, Winston G, Duncan JS, Ourselin S, A symmetric block-matching framework for global registration, Proc.SPIE 2014, Pages: 90341D, DOI:10.1117/12.2043652 https://doi.org/10.1117/12.2043652 [doi]
11. Syková E, Nicholson C. Diffusion in brain extracellular space. Physiol Rev. 2008 Oct;88(4):1277-340. doi: 10.1152/physrev.00027.2007. PMID: 18923183; PMCID: PMC2785730. [doi][pmid]