Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
463-03-002 ISMRM Abstract

Oxygenation and Perfusion Pattern of Grey Matter and White Matter in Ischemic Stroke

Primary: Neuro - Stroke and Cerebrovascular Disorders
Secondary: Neuro - Gray Matter
463-03-002 · Metabolic Parameters in Stroke · Tuesday, 12 May, 1:40 PM–2:35 PM · Digital Posters Row D
Keywords: Oxygen extraction fraction Cerebral metabolic rate of oxygen Ischemic Stroke Neurovascular coupling Perfusion MRI
Accepted
Di Wu 1, Changliang Su2, Jiayu Fang1, Zuwu Ai1, Junxiong Xie3, Yaqin Zhang3, Wenzhen Zhu4
1Department of Radiology, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, China
2Department of Radiology, Sun yat-sen university cancer center, Guangzhou, China
3The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, China
4Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1095, Wuhan, China
Presenting Author: Di Wu

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References

1. Fan AP, Khalil AA, Fiebach JB, et al. Elevated brain oxygen extraction fraction measured by MRI susceptibility relates to perfusion status in acute ischemic stroke. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2020; 40: 539-551. 2019/02/09. DOI: 10.1177/0271678X19827944. [doi]
2. Meng Y, Li CX and Zhang X. Quantitative Evaluation of Oxygen Extraction Fraction Changes in the Monkey Brain during Acute Stroke by Using Quantitative Susceptibility Mapping. Life (Basel) 2023; 13 2023/04/28. DOI: 10.3390/life13041008. [doi]
3. Wu D, Zhou Y, Cho J, et al. The Spatiotemporal Evolution of MRI-Derived Oxygen Extraction Fraction and Perfusion in Ischemic Stroke. Frontiers in neuroscience 2021; 15: 716031. 2021/09/07. DOI: 10.3389/fnins.2021.716031. [doi]
4. Seiler A, Blockley NP, Deichmann R, et al. The relationship between blood flow impairment and oxygen depletion in acute ischemic stroke imaged with magnetic resonance imaging. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2019; 39: 454-465. 2017/09/21. DOI: 10.1177/0271678x17732448. [doi]
5. Zhang J, Cho J, Zhou D, et al. Quantitative susceptibility mapping-based cerebral metabolic rate of oxygen mapping with minimum local variance. Magnetic resonance in medicine 2018; 79: 172-179. DOI: 10.1002/mrm.26657. [doi]
6. Gaser C, Dahnke R, Thompson PM, et al. CAT - A Computational Anatomy Toolbox for the Analysis of Structural MRI Data. 2023. DOI: 10.1101/2022.06.11.495736. [doi]
7. Dirnagl U, Iadecola C and Moskowitz MA. Pathobiology of ischaemic stroke: an integrated view. Trends in neurosciences 1999; 22: 391-397. 1999/08/11. DOI: 10.1016/s0166-2236(99)01401-0. [doi]
8. Wu D, Li Y, Zhang S, et al. Trajectories and sex differences of brain structure, oxygenation and perfusion functions in normal aging. Neuroimage 2024; 302: 120903. 2024/10/27. DOI: 10.1016/j.neuroimage.2024.120903. [doi]
9. Li JX, Zeng QZ, Luo X, et al. Decoupling of Regional Cerebral Blood Flow and Brain Function Along the Alzheimer's Disease Continuum. J Alzheimers Dis 2023; 95: 287-298. DOI: 10.3233/Jad-230503. [doi]

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http://echo.ismrm.org/p/ISMRM2026/463-03-002