Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
531-01-017 / 531-01-017 ISMRM Abstract

UTE MRI-Based Quantification of Femoral Trabecular Bone Reveals Age- and Osteoporosis-related changes

Accepted
Jisook Yi1,2, Arya A Suprana1, Yankai Meng1,3, Yajun Ma4, Eric Y Chang1, Gina N Woods5, Charles Ginsberg6, Saeed Jerban1, Jiang Du4
1Department of Radiology, University of California, San Diego, United States of America
2Department of Radiology, Inje University Haeundae Paik Hospital, Busan, Korea, Republic of
3Department of Radiology, Affiliated Hospital of Xuzhou Medical University, Xuzhou, China
4University of California, San Diego, United States of America
5Department of Medicine, University of California, San Diego, United States of America
6Division of Nephrology-Hypertension, University of California, San Diego, United States of America
Presenting Author: Soo Hyun Shin

Synopsis

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References

1. Wehrli FW, Song HK, Saha PK, Wright AC. Quantitative MRI for the assessment of bone structure and function. NMR in Biomed 2006; 19:731-764.
2. Shin SH, Chae HD, Suprana A, et al. UTE MRI technical developments and applications in osteoporosis: A review. Frontiers in Endocrinology 2025;16:1510010.
3. Bae WC, Chen PC, Chung CB, Masuda K, DLima D, Du J. Quantitative ultrashort echo time (UTE) MRI of human cortical bone: correlation with porosity and biomechanical properties. J Bone Miner Res 2012; 27:848-857.
4. Horch RA, Gochberg DF, Nyman JF, Does MD. Non-invasive predictors of human cortical bone mechanical properties: T(2)-discriminated H NMR compared with high resolution X-ray. PLoS One 2011; 6:e16359.
5. Jerban S, Ma Y, Wei Z, et al. Quantitative magnetic resonance imaging of cortical and trabecular bone. Semin Musculoskelet Radiol. 2020 24(4):381-401.
6. Jerban S, Moazamian D, Mohammadi HS, et al. More accurate trabecular bone imaging using UTE MRI at the resonance frequency of fat. Bone. 2024:184:117096.
7. Li, J, Liao JW, Li W, et al. Assessment of osteoporosis in lumbar spine: In vivo quantitative MR imaging of collagen-bound water in trabecular bone. Front Endocrinol (Lausanne) 2022 16:13:801930.
8. Suprana A, Wu J, Wang J, Sah RL, Ma Y, Jerban S, Woods G, Ginsberg C, Du J. Using novel biomarkers from 3D ultrashort echo time (UTE) MRI techniques to detect bone losses associated with osteopenia, osteoporosis, and chronic kidney disease-mineral and bone disorder. ASBMR Annual Meeting, Seattle, Washington, USA, September 4-9, 2025, #238.

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