Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
663-02-003 ISMRM Abstract

Free water fraction as neuroinflammatory biomarker in chronic pain using NODDI

Primary: Diffusion - DWI/DTI/DKI
Secondary: Diffusion - Microstructure
663-02-003 · Diffusion: DWI/DTI/DKI · Thursday, 14 May, 9:25 AM–10:20 AM · Digital Posters Row D
Keywords: Free-water DTI model Node reporting and data system Chronic pain
Accepted
Chisondi S Warioba1, Yiyu Wang1,2, Christine S W Law1,2, Kenneth Weber 1, Sean Mackey1,2
1Department of Anesthesiology, Perioperative and Pain Medicine, Stanford University, Stanford, United States of America
2Department of Anesthesiology, Perioperative and Pain Medicine, Stanford Medicine, Stanford, United States of America
Presenting Author: Kenneth Weber

Synopsis

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References

1. Bautin P, et al. What has brain diffusion magnetic resonance imaging taught us about chronic primarypain: a narrative review. Pain. 2025;166(2):243-261.
2. Xiong Y, et al. Application of neurite orientation dispersion and density imaging in characterizing brainmicrostructural changes in classical trigeminal neuralgia. Pain. 2025;166(10):2332-2341.
3. Zhang H, et al. NODDI: practical in vivo neurite orientation dispersion and density imaging of the humanbrain. Neuroimage. 2012;61(4):1000-1016.
4. Smith SM, et al. Tract-based spatial statistics: voxelwise analysis of multi-subject diffusion data. Neuroimage. 2006;31(4):1487-1505.
5. Alshelh Z, et al. Neuroimmune signatures in chronic low back pain subtypes. Brain. 2022;145(3):10981110.

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/663-02-003