Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
463-02-004 ISMRM Abstract

Alterations of brain network topology and structural-functional coupling in post-stroke aphasia

Primary: Neuro - Stroke and Cerebrovascular Disorders
Secondary: Brain Function and fMRI - Functional Connectivity
463-02-004 · Imaging Stroke Recovery: From Microstructure to Personalized Therapy · Tuesday, 12 May, 9:15 AM–10:10 AM · Digital Posters Row D
Keywords: Stroke Multi-modal MRI Aphasia Structure function coupling 3T MRI
Accepted
Guihua Xu 1, Yongsheng Wu1, Rui Zhu1, Junyu Qu1, Wenwen Xu1, Yunqi Ju1, Jiaxiang xin2,3,4, Dawei Wang1,5,6
1Department of Radiology, Qilu Hospital of Shandong University, Qilu Medical Imaging Institute of Shandong University, Jinan,China, China
2MR Collaborations, Siemens Healthineers Ltd., Shanghai, China
3Magnetic Resonance Research Collaboration, Siemens Healthineers Ltd, Shanghai, China
4Magnetic Resonance Research Collaboration, Shanghai, China
5Shandong Key Laboratory for Magnetic Field-free Medicine and Functional Imaging, Institute of Magnetic Field-free Medicine and Functional Imaging, Shandong University, Jinan 250014, China
6National Innovation Platform for Industry-Education Integration in Medicine-Engineering Interdisciplinary, Shandong University, Jinan 250014, China
Presenting Author: Guihua Xu

Synopsis

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References

1. GBD 2019 Stroke Collaborators. Global, regional, and national burden of stroke and its risk factors, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019. Lancet Neurol 20, 795–820 (2021) doi: 10.1016/S1474-4422(21)00252-0. [doi]
2. Stockert, A. et al. Dynamics of language reorganization after left temporo-parietal and frontal stroke. Brain 143, 844–861 (2020) doi: 10.1093/brain/awaa023. [doi]
3. Tang, H. et al. Remote cortical atrophy and language outcomes after chronic left subcortical stroke with aphasia. Front Neurosci 16, 853169 (2022) doi: 10.3389/fnins.2022.853169. [doi]
4. Xu, G. et al. Altered Dynamic Functional Network Connectivity in Post-Stroke Aphasia. Ann Clin Transl Neurol (2025) doi:10.1002/acn3.70194. [doi]
5. Baum, G. L. et al. Development of structure-function coupling in human brain networks during youth. Proc Natl Acad Sci U S A 117, 771–778 (2020) doi: 10.1073/pnas. [doi]
6. Qu, J. et al. Abnormal Structural–Functional Coupling and MRI Alterations of Brain Network Topology in Progressive Supranuclear Palsy. Journal of Magnetic Resonance Imaging (2024) doi:10.1002/jmri.29620. [doi]
7. Xing, S. et al. Right hemisphere grey matter structure and language outcomes in chronic left hemisphere stroke. Brain 139, 227–241 (2016) doi: 10.1093/brain/awv323. [doi]
8. Wang, S. et al. Decoupling of Structural and Functional Connectivity in Hubs and Cognitive Impairment After Mild Traumatic Brain Injury. Brain Connect 11, 745–758 (2021) doi: 10.1089/brain.2020.0852. [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/463-02-004