Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
469-04-008 ISMRM Abstract

A Novel Dynamic 31P MRS Method for Assessment of pH-Resolved ATP Synthesis in Exercising Skeletal Muscle at 7T

Primary: Musculoskeletal - Muscle
Secondary: Analysis Methods - Segmentation and Detection
469-04-008 · MRI and MRS in Muscle in Health and Disease · Tuesday, 12 May, 2:35 PM–3:30 PM · Digital Posters Row J
Keywords: Exercise Energy metabolism 31P-MRS Spectral quantification Mitochondrial dysfunction
Accepted
Jimin Ren 1,2, Neha Patel1, Ross Querry3, Staci Shearin3, Wanpen Vongpatanasin1
1University of Texas Southwestern Medical Center, Dallas, United States of America
2Department of Radiology, University of Texas Southwestern Medical Center, Dallas, United States of America
3Department of Physical Therapy, University of Texas Southwestern Medical Center, Dallas, United States of America
Presenting Author: Jimin Ren

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References

1. (31) P magnetic resonance spectroscopy in skeletal muscle: Experts' consensus recommendations. Meyerspeer M, Boesch C, Cameron D, Dezortová M, Forbes SC, Heerschap A, Jeneson JAL, Kan HE, Kent J, Layec G, Prompers JJ, Reyngoudt H, Sleigh A, Valkovič L, Kemp GJ; Experts' Working Group on 31P MR Spectroscopy of Skeletal Muscle. NMR Biomed. 2020;34(5):e4246. doi: 10.1002/nbm.4246. PMCID: PMC8243949 [doi]
2. Ren J, Patel N, Johnson T, Querry R, Shearin S. Skeletal Muscle 31P Magnetic Resonance Spectroscopy Study of Patients with Parkinson’s Disease: Energy Metabolism and Exercise Performance. Diagnostics 2025;15:2573. PMID: 41153248 DOI: 10.3390/diagnostics15202573 diagnostics15202573 [doi] [pmid]
3. Magnetic resonance reveals mitochondrial dysfunction and muscle remodelling in spinal muscular atrophy. Habets LE, Bartels B, Asselman FL, Hooijmans MT, van den Berg S, Nederveen AJ, van der Pol WL, Jeneson JAL. Brain. 2022;145(4):1422-1435. doi: 10.1093/brain/awab411. PMCID: PMC9128825 [doi]
4. Prompers JJ, Wessels B, Kemp GJ, Nicolay K. MITOCHONDRIA: investigation of in vivo muscle mitochondrial function by 31P magnetic resonance spectroscopy. Int J Biochem Cell Biol. 2014;50:67-72. doi: 10.1016/j.biocel.2014.02.014. [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/469-04-008