Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
470-05-109 ISMRM Abstract

Whole-brain mapping of diffusion fibre response functions using hybrid MRI–microscopy modelling

Primary: Diffusion - Microstructure
Secondary: Diffusion - Diffusion Modeling
470-05-109 · Advanced Diffusion Modeling for Microstructure Mapping · Tuesday, 12 May, 1:40 PM–2:35 PM · Traditional Posters | Exhibition Hall
Keywords: Microstructure Diffusion-weighted MRI Constrained spherical deconvolution Fibre response function
Accepted
Silei Zhu1, Saad Jbabdi1, Karla Miller1, Amy Howard 1,2
1Oxford Centre for Integrative Neuroimaging (FMRIB Centre), University of Oxford, Oxford, United Kingdom
2Department of Bioengineering, Imperial College London, London, United Kingdom
Presenting Author: Amy Howard

Synopsis

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References

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2. Tournier JD, Calamante F, Connelly A. Robust determination of the fibre orientation distribution in diffusion MRI: non-negativity constrained super-resolved spherical deconvolution. Neuroimage. 2007 May 1;35(4):1459-72. doi: 10.1016/j.neuroimage.2007.02.016. [doi]
3. Howard AF, Mollink J, Kleinnijenhuis M, Pallebage-Gamarallage M, Bastiani M, Cottaar M, Miller KL, Jbabdi S. Joint modelling of diffusion MRI and microscopy. Neuroimage. 2019 Nov 1;201:116014. doi: 10.1016/j.neuroimage.2019.116014. [doi]
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5. Howard AFD, Huszar IN, Smart A, Cottaar M, Daubney G, Hanayik T, Khrapitchev AA, Mars RB, Mollink J, Scott C, Sibson NR, Sallet J, Jbabdi S, Miller KL. An open resource combining multi-contrast MRI and microscopy in the macaque brain. Nat Commun. 2023 Jul 19;14(1):4320. doi: 10.1038/s41467-023-39916-1. PMID: 37468455; PMCID: PMC10356772. [doi] [pmid]
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10. Tournier JD, Smith R, Raffelt D, Tabbara R, Dhollander T, Pietsch M, Christiaens D, Jeurissen B, Yeh CH, Connelly A. MRtrix3: A fast, flexible and open software framework for medical image processing and visualisation. Neuroimage. 2019 Nov 15;202:116137. doi: 10.1016/j.neuroimage.2019.116137. Epub 2019 Aug 29. PMID: 31473352. [doi] [pmid]
11. Aboitiz F, Scheibel AB, Fisher RS, Zaidel E. Fiber composition of the human corpus callosum. Brain Res. 1992 Dec 11;598(1-2):143-53. doi: 10.1016/0006-8993(92)90178-c. PMID: 1486477. [doi] [pmid]

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http://echo.ismrm.org/p/ISMRM2026/470-05-109