662-01-013 ISMRM Abstract

Zooming into Hippocampus Subfield and Architectural Alterations with Aging

Primary: Neuro - Aging

Secondary: Neuro - Epilepsy

662-01-013 · Advanced Quantitative and Diffusion MRI for Epilepsy: From Lesion Detection to Clinical Translation · Thursday, 14 May, 8:30 AM–9:25 AM · Digital Posters Row C

Keywords: Aging High-Resolution MRI Hippocampal subfields Subfield segmentation Architecture

Accepted

Rittika Dutta¹, Archita Khatua¹, Pratiti Phukan¹, Niraj K Gupta¹, Neha Yadav ¹, Vivek Tiwari¹

¹Department of Biological Sciences, Indian Institute of Science Education and Research (IISER) Berhampur, Odisha, India

Presenting Author: Neha Yadav

Synopsis

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References

1. Strange BA, Witter MP, Lein ES, Moser EI. Functional organization of the hippocampal longitudinal axis. Nat Rev Neurosci. 2014;15(10):655-669. doi:10.1038/nrn3785 [doi]

2. Ghaderi S, Mohammadi S, Fatehi F; Alzheimer's Disease Neuroimaging Initiative. Mapping divergent subfield-specific hippocampal degeneration in mild cognitive impairment continuum: Volumetric, cognitive, and genetic predictors of accelerated hippocampal biological aging. CNS Neurosci Ther. 2025;31(7):e70548. doi:10.1111/cns.70548 [doi]

3. Gohel S, Chan CC, Baptista I, Szeszko PR. Age-associated trajectories of hippocampus subregion volumes from childhood through later adulthood. Neurobiol Aging. 2025;156:73-84. doi:10.1016/j.neurobiolaging.2025.08.002. [doi]

4. Mareckova K, Devenyi GA, Andryskova L, Chakravarty MM, Nikolova YS. Maturation of hippocampal subfields in young adulthood and its relationship with cognition. Hum Brain Mapp. 2025;46(11):e70296. doi:10.1002/hbm.70296. [doi]

5. Yadav, N., Gupta, N.K., Thakar, D. et al. Magnitude and kinetics of a set of neuroanatomic volume and thickness together with white matter hyperintensity is definitive of cognitive status and brain age. Transl Psychiatry 14, 389 (2024). https://doi.org/10.1038/s41398-024-03097-2 [doi]

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http://echo.ismrm.org/p/ISMRM2026/662-01-013