Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
363-01-014 ISMRM Abstract

OGSE-Derived Microstructural Biomarkers Predict Cognitive Improvement in Idiopathic Normal Pressure Hydrocephalus

Primary: Neuro - Hydrocephalus
Secondary: Diffusion - Microstructure
363-01-014 · Neurological Application of Advanced Diffusion and Quantitative MRI · Monday, 11 May, 8:20 AM–9:15 AM · Digital Posters Row D
Keywords: Cognition Neuroimaging Idiopathic normal pressure hydrocephalus Diffusion magnetic resonance imaging
Accepted
Che zhang1, busharemu reheman1, Xinyi Bai1, Chen Zhang2, Zhang Zhang1, Huijie Wei3, Thorsten Feiweier4, Ningnannan Zhang 1
1Department of Radiology and Tianjin Key Laboratory of Functional Imaging, Tianjin Medical University General Hospital, Tianjin, China
2MR Research Collaboration, Siemens Healthineers, Beijing, China
3Department of Neurosurgery, Tianjin Medical University General Hospital, Tianjin, China
4MR Research and Clinical Translation, Siemens Healthineers AG, Erlangen, Germany
Presenting Author: Ningnannan Zhang

Synopsis

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References

1. Kim W, St Brice K, Olvera-Castro JF, et al. Non-invasive versus invasive techniques for predicting idiopathic normal-pressure hydrocephalus in shunt-responsive patients. Neurosurg Rev. 2025;48(1):741. DOI:10.1007/s10143-025-03895-2. PMID: 41145826. [doi] [pmid]
2. Zhu A, Michael ES, Li H, et al. Engineering clinical translation of OGSE diffusion MRI[J]. Magn Reson Med, 2025, 94(3): 913-936. DOI: 10.1002/mrm.30510. PMID: 40331336. [doi] [pmid]
3. Rau A, Reisert M, Kellner E, et al. Increased interstitial fluid in periventricular and deep white matter hyperintensities in patients with suspected idiopathic normal pressure hydrocephalus[J]. Sci Rep, 2021, 11(1): 19552. DOI: 10.1038/s41598-021-98054-0. PMID: 34599204. [doi] [pmid]
4. Jugé L, Pong AC, Bongers A, et al. Changes in rat brain tissue microstructure and stiffness during the development of experimental obstructive hydrocephalus[J/OL]. PLoS One, 2016, 11(2): e0148652[2024-05-25]. DOI: 10.1371/journal.pone.0148652. PMID: 26848844. [doi] [pmid]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/363-01-014